Department of Clinical Dietetics, Faculty of Health Sciences, Medical University of Warsaw, E Ciołka Str. 27, 01-445 Warsaw, Poland.
Nutrients. 2020 Nov 7;12(11):3419. doi: 10.3390/nu12113419.
The Western, diet rich in acidogenic foods (e.g., meat, fish and cheese) and low in alkaline foods (e.g., vegetables, fruits and legumes), is deemed to be a cause of endogenous acid production and elevated dietary acid load (DAL), which is a potential cause of metabolic acidosis. Multiple authors have suggested that such a dietary pattern increases the excretion of calcium and magnesium, as well as cortisol secretion. In addition, it is associated with decreased citrate excretion. All of these seem to increase blood pressure and insulin resistance and may contribute to the development of cardiometabolic disorders. However, there are inconsistencies in the results of the studies conducted. Therefore, this narrative literature review aims to present the outcomes of studies performed in recent years that investigated the association between DAL and the following cardiometabolic risk factors: blood pressure, hypertension, carbohydrate metabolism and lipid profile. Study outcomes are divided into (i) statistically significant positive association, (ii) statistically significant inverse association, and (iii) no statistically significant association.
西方饮食富含产酸性食物（例如肉、鱼和奶酪），而碱性食物（例如蔬菜、水果和豆类）含量较低，被认为是内源性酸生成和膳食酸负荷（DAL）升高的原因，这可能是代谢性酸中毒的一个潜在原因。多位作者提出，这种饮食模式会增加钙和镁的排泄以及皮质醇的分泌。此外，它还与柠檬酸排泄减少有关。所有这些似乎都会增加血压和胰岛素抵抗，并可能导致代谢综合征相关疾病的发生。然而，已进行的研究结果存在不一致性。因此，本叙述性文献综述旨在介绍近年来进行的研究结果，这些研究调查了 DAL 与以下心血管代谢危险因素之间的关系：血压、高血压、碳水化合物代谢和血脂谱。研究结果分为（i）具有统计学意义的正相关，（ii）具有统计学意义的负相关，和（iii）无统计学意义的相关。
