静坐行为模式与老年人的骨密度和身体功能相关：横断面和前瞻性数据。
Sedentary Patterns Are Associated with Bone Mineral Density and Physical Function in Older Adults: Cross-Sectional and Prospective Data.
机构信息
Skeletal Muscle Assessment Laboratory, Department of Physical Education, School of Technology and Sciences, São Paulo State University, São Paulo 19060-900, Brazil.
Post-Graduation Program in Movement Sciences, School of Technology and Sciences, São Paulo State University, São Paulo 19060-900, Brazil.
出版信息
Int J Environ Res Public Health. 2020 Nov 6;17(21):8198. doi: 10.3390/ijerph17218198.
Aging causes some unfavorable morphological and functional changes, such as the decline in bone mineral density (BMD) and physical function. Moderate-to-vigorous physical activity (MVPA) and sedentary time seem to be related with these alterations, but the impact of distinct patterns remains unclear. The aim of this study was to cross-sectionally and prospectively assess the association between objectively measured MVPA and sedentary patterns (bouts and breaks) with BMD and physical function in older adults. The study considered 151 Brazilians (aged ≥ 60 years), out of which 68 participants completed 2-year follow-up measurements. MVPA and sedentary patterns were measured by means of accelerometry, BMD-(total proximal femur and lumbar spine (L1-L4)) by means of dual-energy X-ray absorptiometry (DXA), and physical function-by means of physical tests. In older women, sedentary bouts >60 min were inversely associated with handgrip strength (β = -2.03, 95% CI: from -3.43 to -0.63). The prospective analyses showed that changes in sedentary bouts (20 to 30 min and >60 min) were inversely associated with changes in the lumbar spine's BMD (β = -0.01, 95% CI: from -0.01 to -0.00 and β = -0.03, 95% CI: from -0.06 to -0.01) and the lumbar spine's T-score (β = -0.06, 95% CI: from -0.10 to -0.01 and β = -0.27, 95% CI: from -0.49 to -0.04), respectively. In older women, sedentary patterns are cross-sectionally associated with handgrip strength and prospectively associated with BMD independent of MVPA.
衰老是导致一些不利的形态和功能变化的原因，如骨矿物质密度（BMD）和身体功能下降。适度到剧烈的身体活动（MVPA）和久坐时间似乎与这些变化有关，但不同模式的影响尚不清楚。本研究旨在横断面和前瞻性评估客观测量的 MVPA 和久坐模式（发作和休息）与老年人 BMD 和身体功能的关系。该研究共纳入 151 名巴西人（年龄≥60 岁），其中 68 名参与者完成了 2 年的随访测量。MVPA 和久坐模式通过加速度计测量，BMD（总股骨近端和腰椎（L1-L4））通过双能 X 射线吸收法（DXA）测量，身体功能通过身体测试测量。在老年女性中，久坐发作时间＞60 分钟与握力呈负相关（β=-2.03，95%CI：-3.43 至-0.63）。前瞻性分析显示，久坐发作时间（20-30 分钟和＞60 分钟）的变化与腰椎 BMD（β=-0.01，95%CI：-0.01 至-0.00 和β=-0.03，95%CI：-0.06 至-0.01）和腰椎 T 评分（β=-0.06，95%CI：-0.10 至-0.01 和β=-0.27，95%CI：-0.49 至-0.04）的变化呈负相关。在老年女性中，久坐模式与握力呈横断面相关，与 BMD 呈前瞻性相关，与 MVPA 无关。
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