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农村阿萨姆邦妊娠糖尿病的流行情况及预测因素:利用移动医疗单位进行的横断面研究。

Prevalence and predictors of gestational diabetes mellitus in rural Assam: a cross-sectional study using mobile medical units.

机构信息

Clinical Domain, Piramal Swasthya Management and Reseach Institute, Guwahati, Assam, India.

Research and Analysis Wing, Piramal Swasthya Management and Reseach Institute, Hyderabad, Telangana, India

出版信息

BMJ Open. 2020 Nov 10;10(11):e037836. doi: 10.1136/bmjopen-2020-037836.

Abstract

OBJECTIVE

To determine the prevalence and predictors of gestational diabetes mellitus (GDM) in rural Assam, India using a network of Mobile Medical Units.

STUDY DESIGN

A field-based cross-sectional study.

SETTINGS

Rural areas of Assam state, India.

PARTICIPANTS

A total of 1410 pregnant women in gestational age of 24-28 weeks INTERVENTION: Identification of pregnant women in 24-28 weeks of pregnancy from villages and administering them Government of India recommended oral glucose tolerance test for GDM confirmation.

PRIMARY AND SECONDARY OUTCOME MEASURES

Presence of gestational diabetes among pregnant women, risk factors and predictors of GDM.

RESULTS

A total of 1212 pregnant women underwent the oral glucose tolerance test. One hundred and ninety-eight women were ineligible due to existing chronic diseases or very high blood glucose level before the test. The overall GDM prevalence in Assam was 16.67% (95% CI 14.61% to 18.89%). Women aged 26-30 years (adjusted odds ratio, aOR 1.70; CI 1.14 to 2.52), who passed 10th class (aOR 1.58; CI 1.05 to 2.37), belonging to Muslim religion (aOR 1.52; 95% CI 1.05 to 2.21) and above poverty line (aOR 1.38; 95% CI 1.00 to 1.91) had significantly increased likelihood of developing GDM compared with respective baseline groups (p<0.05). Body mass index, gravida and being non-anaemic were non-significant risk factors for GDM. Family history of diabetes (aOR 1.82; 95% CI 1.08 to 3.06) and smoking (aOR 1.61; 95% CI 1.10 to 2.35) were significant and independent predictors of GDM.

CONCLUSION

The prevalence of GDM in rural Assam is high. The mobile medical units may play a significant role in the implementation of GDM screening, diagnosis, treatment to ensure better maternal and foetal health outcomes in rural Assam.

摘要

目的

利用移动医疗单位网络,确定印度阿萨姆邦农村地区妊娠糖尿病(GDM)的患病率和预测因素。

研究设计

基于现场的横断面研究。

设置

印度阿萨姆邦农村地区。

参与者

共 1410 名妊娠 24-28 周的孕妇。

干预措施

从村庄中识别出妊娠 24-28 周的孕妇,并为她们提供印度政府推荐的口服葡萄糖耐量试验(OGTT)以确认 GDM。

主要和次要结局测量

孕妇中妊娠糖尿病的存在、GDM 的危险因素和预测因素。

结果

共有 1212 名孕妇接受了口服葡萄糖耐量试验。由于现有慢性病或试验前血糖水平非常高,198 名妇女不合格。阿萨姆邦的 GDM 总患病率为 16.67%(95%CI 14.61%至 18.89%)。26-30 岁年龄组(调整后的优势比,aOR 1.70;95%CI 1.14 至 2.52)、通过 10 年级考试(aOR 1.58;95%CI 1.05 至 2.37)、属于穆斯林宗教(aOR 1.52;95%CI 1.05 至 2.21)和高于贫困线(aOR 1.38;95%CI 1.00 至 1.91)的妇女与各自的基线组相比,GDM 的发生可能性显著增加(p<0.05)。体重指数、孕次和非贫血均不是 GDM 的显著危险因素。糖尿病家族史(aOR 1.82;95%CI 1.08 至 3.06)和吸烟(aOR 1.61;95%CI 1.10 至 2.35)是 GDM 的显著独立预测因素。

结论

阿萨姆邦农村地区 GDM 的患病率较高。移动医疗单位可能在 GDM 筛查、诊断和治疗的实施中发挥重要作用,以确保阿萨姆邦农村地区母婴健康结局的改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ec46/7656912/fef06e2c4eb4/bmjopen-2020-037836f01.jpg

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