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坦桑尼亚南部农村孕妇妊娠糖尿病的患病率及相关因素

Prevalence and associated factors of gestational diabetes mellitus among rural pregnant women in southern Tanzania.

作者信息

Mghanga Fabian P, Maduhu Elia A, Nyawale Helmut A

机构信息

Department of Internal Medicine, Faculty of Medicine, Archbishop James University College, Songea, Tanzania.

Department of Community Medicine, Faculty of Medicine, Archbishop James University College, Songea, Tanzania.

出版信息

Ghana Med J. 2020 Jun;54(2):82-87. doi: 10.4314/gmj.v54i2.5.

Abstract

INTRODUCTION

Gestational diabetes mellitus (GDM) is a potential risk factor for both maternal and foetal complications during pregnancy. This study aimed to determine the prevalence and factors associated with GDM among pregnant women in Southern Tanzania.

METHODS

A cross-sectional study was conducted among 612 randomly selected pregnant women attending routine antenatal clinics in Southern Tanzania from September to October 2017. Detailed medical and gynaecological history was taken using pre-tested questionnaires. Blood samples were collected for fasting and oral glucose tolerance tests. We diagnosed GDM using the World Health Organization 2013 diagnostic criteria for diabetes mellitus. We performed statistical analysis using SPSS v24.0. Possible associations and statistical significance were measured using odds ratio at 95% confidence interval, and -values of <0.05 were considered statistically significant.

RESULTS

The mean age and standard deviation of the study subjects was 24.5±6.9 years. The prevalence of GDM was 4.3%. GDM was significantly associated with: being overweight or obese (p<0.001), past history of pre-term delivery (), past history of stillbirths (), history of macrosmia (), alcohol consumption (p=0.001), and having a first degree relative with diabetes mellitus ().

CONCLUSION

Prevalence of Gestational Diabetes Mellitus is low in this study setting. We recommend close attention to at risk women to prevent development of GDM.

FUNDING

None declared.

摘要

引言

妊娠期糖尿病(GDM)是孕期母婴并发症的一个潜在风险因素。本研究旨在确定坦桑尼亚南部孕妇中GDM的患病率及其相关因素。

方法

2017年9月至10月,对在坦桑尼亚南部常规产前诊所就诊的612名随机选取的孕妇进行了一项横断面研究。使用预先测试的问卷收集详细的医学和妇科病史。采集血样进行空腹和口服葡萄糖耐量试验。我们采用世界卫生组织2013年糖尿病诊断标准诊断GDM。使用SPSS v24.0进行统计分析。采用95%置信区间的比值比测量可能的关联和统计学意义,P值<0.05被认为具有统计学意义。

结果

研究对象的平均年龄和标准差为24.5±6.9岁。GDM的患病率为4.3%。GDM与以下因素显著相关:超重或肥胖(P<0.001)、既往早产史()、既往死产史()、巨大儿史()、饮酒(P=0.001)以及有糖尿病一级亲属()。

结论

在本研究环境中,妊娠期糖尿病的患病率较低。我们建议密切关注高危女性,以预防GDM的发生。

资金来源

未声明。

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