Kilimanjaro Christian Medical University College, Moshi, Tanzania.
Department of Obstetrics & Gynaecology, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Trop Med Int Health. 2018 Feb;23(2):236-242. doi: 10.1111/tmi.13018. Epub 2017 Dec 13.
To determine the prevalence and predictors of gestational diabetes mellitus (GDM) as well as acceptability of returning for glucose tolerance testing among pregnant women in Moshi municipality, northern Tanzania.
Cross-sectional study from October 2015 to April 2016 among women with gestation age of 24-28 weeks of pregnancy attending at Kilimanjaro Christian Medical Centre (KCMC) referral hospital, Majengo and Pasua Health Centres. Women were interviewed and requested to return the next day (window within a month, depending on gestational age) for fasting plasma glucose (FPG) testing, followed immediately by a 75 g oral glucose tolerance test (OGTT). GDM was diagnosed using the 2013 WHO criteria. Logistic regression was conducted to reveal independent predictors for GDM.
Of 433 interviewed women, 100 (23%) did not return for FPG and OGTT testing. The prevalence of GDM among the 333 screened women was 19.5%, and 3% had diabetes in pregnancy (DIP). GDM was significantly associated with age ≥35 years (adjusted OR 6.75), pre-pregnancy obesity (AOR 2.22) and history of abortion (AOR 2.36).
Prevalence of GDM is high in Moshi. We recommend introduction of routine screening for hyperglycaemia during pregnancy along with strategies for follow-up to prevent long-term effects of GDM and DIP in women and their children.
确定坦桑尼亚北部莫希市孕妇妊娠糖尿病(GDM)的患病率和预测因素,以及孕妇对葡萄糖耐量试验的接受程度。
2015 年 10 月至 2016 年 4 月期间,对在乞力马扎罗基督教医学中心(KCMC)转诊医院、Majengo 和 Pasua 保健中心妊娠龄为 24-28 周的孕妇进行横断面研究。对妇女进行访谈,并要求她们在第二天(一个月内的窗口期,取决于妊娠龄)返回进行空腹血浆葡萄糖(FPG)检测,然后立即进行 75g 口服葡萄糖耐量试验(OGTT)。使用 2013 年世卫组织标准诊断 GDM。采用逻辑回归分析揭示 GDM 的独立预测因素。
在接受访谈的 433 名妇女中,有 100 名(23%)未返回进行 FPG 和 OGTT 检测。在 333 名筛查妇女中,GDM 的患病率为 19.5%,妊娠糖尿病(DIP)为 3%。GDM 与年龄≥35 岁(调整后的 OR 6.75)、孕前肥胖(AOR 2.22)和流产史(AOR 2.36)显著相关。
莫希的 GDM 患病率很高。我们建议在怀孕期间常规筛查高血糖,并制定后续策略,以预防 GDM 和 DIP 对妇女及其子女的长期影响。