Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, India.
Department of Biochemistry, All India Institute of Medical Sciences, New Delhi, India.
WHO South East Asia J Public Health. 2023 Jul 1;12(2):104-109. doi: 10.4103/WHO-SEAJPH.WHO-SEAJPH_113_22. Epub 2024 Jan 19.
High prevalence of Vitamin D deficiency has been reported among selective population, but its population prevalence from representative adult population is lacking in India. The aim of this study was to estimate the prevalence and identify the correlates of Vitamin D deficiency among urban and rural areas of the National Capital Region (NCR) of Delhi, India. Serum Vitamin D levels of 1403 adults (aged 30 years above), 702 from urban and 701 from rural NCR of Delhi, who participated in a representative cross-sectional survey were measured using the quantitative chemiluminescent immunoassay method. The prevalence of Vitamin D deficiency was classified as severe deficient, and insufficient at three serum levels of 25-hydroxyvitamin D-<10, 10-<20, and 20-<30 ng/mL, respectively. The median (interquartile range) 25-hydroxyvitamin D levels in urban and rural areas were 7.7 (5.2, 10.8) ng/mL and 16.2 (10.9, 22.3) ng/mL, respectively. The prevalence of Vitamin D severe deficiency, deficiency, and insufficiency in urban areas were 71%, 27%, and 2%, respectively. The corresponding prevalence in rural areas was 20%, 47%, and 25%. Urban location (odds ratio [OR] [95% confidence interval [CI]: 11.7 [8.6, 15.9]), female gender (OR [95% CI]: 1.5 [1.1, 2.2]), and abdominal obesity (OR [95% CI]:1.5 [1.1, 2.0]) were independently associated with severe deficiency. This study revealed a high prevalence of severe vitamin deficiency among the adult living in NCR, more so among urban areas, women, and obese.
在特定人群中，维生素 D 缺乏症的患病率较高，但在印度，缺乏代表性的成年人的患病率数据。本研究旨在评估印度德里国家首都地区（NCR）城乡地区成年人维生素 D 缺乏症的患病率，并确定其相关因素。采用定量化学发光免疫分析法检测了 1403 名年龄在 30 岁以上的成年人（其中 702 名来自城市，701 名来自农村）的血清维生素 D 水平。将血清 25-羟维生素 D 水平<10、10-<20 和 20-<30ng/ml 分别定义为严重缺乏、不足和缺乏，以此来评估维生素 D 缺乏症的患病率。城市和农村地区的血清 25-羟维生素 D 中位数（四分位距）分别为 7.7（5.2，10.8）ng/ml 和 16.2（10.9，22.3）ng/ml。城市地区维生素 D 严重缺乏、缺乏和不足的患病率分别为 71%、27%和 2%，农村地区的相应患病率分别为 20%、47%和 25%。城市居住环境（比值比 [OR] [95%置信区间 [CI]：11.7 [8.6，15.9]）、女性（OR [95% CI]：1.5 [1.1，2.2]）和腹部肥胖（OR [95% CI]：1.5 [1.1，2.0]）与严重缺乏独立相关。本研究显示，居住在 NCR 的成年人严重维生素缺乏症的患病率较高，城市地区、女性和肥胖者更为严重。
