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MIS-C 与 SARS-CoV-2 感染后之谜。

The Mystery of MIS-C Post-SARS-CoV-2 Infection.

机构信息

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA; Department of Pediatrics, Yale University School of Medicine, New Haven, CT, USA.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

出版信息

Trends Microbiol. 2020 Dec;28(12):956-958. doi: 10.1016/j.tim.2020.10.004. Epub 2020 Oct 14.

Abstract

Following emergence of the coronavirus disease 2019 (COVID-19) pandemic, a surge in the life-threatening illness now termed 'multisystem inflammatory syndrome in children' (MIS-C) has raised questions about the unique effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in children and adolescents. Two important new studies by Consiglio et al. and Gruber et al. have begun to shine light on the immune drivers of this enigmatic disease.

摘要

随着 2019 年冠状病毒病(COVID-19)大流行的出现,一种现在称为“儿童多系统炎症综合征”(MIS-C)的危及生命的疾病激增,这引发了人们对严重急性呼吸综合征冠状病毒 2(SARS-CoV-2)在儿童和青少年中独特影响的疑问。Consiglio 等人和 Gruber 等人的两项重要的新研究开始揭示这种神秘疾病的免疫驱动因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6ed1/7556780/7feb556ed017/gr1_lrg.jpg

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