Key Laboratory of Bacteriology, Ministry of Agriculture, Nanjing, China.
College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Antimicrob Agents Chemother. 2021 Jan 20;65(2). doi: 10.1128/AAC.01716-20.
Integrative conjugative elements (ICEs) are a kind of novel self-transmissible mobile genetic element. In this study, a novel ICE was identified in () We confirmed that it could mediate the migration of antimicrobial resistance genes in and found that there may have been a transferring potential between different serovar strains of These findings demonstrate that the ICE is crucial to the horizontal transfer of antimicrobial resistance among strains.
整合接合元件（ICEs）是一种新型的自我可转移的移动遗传元件。在本研究中，我们在 （）中鉴定出了一种新型的 ICE。我们证实它可以介导抗菌药物耐药基因在 （）中的迁移，并发现不同血清型菌株的 （）之间可能存在转移潜能。这些发现表明 ICE 对于 （）菌株中抗菌药物耐药基因的水平转移至关重要。
