Research Centre of Biotechnology of the Russian Academy of Sciences, Leninsky prospect, 33, build. 2, 119071 Moscow, Russia.
Research Centre of Biotechnology of the Russian Academy of Sciences, Leninsky prospect, 33, build. 2, 119071 Moscow, Russia.
Int J Biol Macromol. 2021 Jan 15;167:1319-1328. doi: 10.1016/j.ijbiomac.2020.11.086. Epub 2020 Nov 14.
Interest in insects as a source of valuable biologically active substances has significantly increased over the past few years. Insects serve as an alternative source of chitin, which forms up to 40% of their exoskeleton. Chitosan, a deacetylated derivative of chitin, attracts the attention of scientists due to its unique properties (sorption, antimicrobial, film-forming, wound healing). Furthermore, some insect species are unique and can be used to obtain chitin- and chitosan-melanin complexes in the later stages of ontogenesis. Due to the synergistic effect, chitosan and melanin can enhance each other's biological activity, providing a wide range of potential applications.
近年来,人们对昆虫作为有价值的生物活性物质来源的兴趣显著增加。昆虫是甲壳素的替代来源,甲壳素构成了它们外骨骼的 40%。壳聚糖是甲壳素的去乙酰化衍生物,由于其独特的性质(吸附、抗菌、成膜、愈合伤口)而引起了科学家的关注。此外,一些昆虫物种是独特的,可以在个体发育的后期用于获得壳聚糖和黑色素的复合物。由于协同效应,壳聚糖和黑色素可以增强彼此的生物活性,提供广泛的潜在应用。