Faculty of Chemistry, University of Gdansk, Sobieskiego 18/19, PL-80-952 Gdansk, Poland.
Mar Drugs. 2010 Apr 29;8(5):1567-636. doi: 10.3390/md8051567.
Chitin, the second most important natural polymer in the world, and its N-deacetylated derivative chitosan, have been identified as versatile biopolymers for a broad range of applications in medicine, agriculture and the food industry. Two of the main reasons for this are firstly the unique chemical, physicochemical and biological properties of chitin and chitosan, and secondly the unlimited supply of raw materials for their production. These polymers exhibit widely differing physicochemical properties depending on the chitin source and the conditions of chitosan production. The presence of reactive functional groups as well as the polysaccharide nature of these biopolymers enables them to undergo diverse chemical modifications. A complete chemical and physicochemical characterization of chitin, chitosan and their derivatives is not possible without using spectroscopic techniques. This review focuses on the application of spectroscopic methods for the structural analysis of these compounds.
甲壳素是世界上第二大重要的天然聚合物，其 N-脱乙酰基衍生物壳聚糖已被确定为在医学、农业和食品工业中具有广泛应用的多功能生物聚合物。其原因有二，一是甲壳素和壳聚糖具有独特的化学、物理化学和生物学特性，二是其生产原料供应无限。这些聚合物的物理化学性质因甲壳素来源和壳聚糖生产条件而异。这些生物聚合物存在反应性官能团以及多糖性质，使其能够进行多种化学修饰。如果不使用光谱技术，就不可能对甲壳素、壳聚糖及其衍生物进行完整的化学和物理化学表征。本综述重点介绍了光谱方法在这些化合物结构分析中的应用。
