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采用三维多孔钛合金椎间融合器和钛涂层聚醚醚酮椎间融合器行腰椎后路椎间融合术后短期影像学和临床疗效的比较

Comparison of Short-Term Radiographical and Clinical Outcomes After Posterior Lumbar Interbody Fusion With a 3D Porous Titanium Alloy Cage and a Titanium-Coated PEEK Cage.

作者信息

Makino Takahiro, Takenaka Shota, Sakai Yusuke, Yoshikawa Hideki, Kaito Takashi

机构信息

Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

出版信息

Global Spine J. 2022 Jun;12(5):931-939. doi: 10.1177/2192568220972334. Epub 2020 Nov 18.

Abstract

STUDY DESIGN

Clinical case series.

OBJECTIVES

To compare the short-term (≤1 year) radiographical and clinical outcomes between posterior lumbar interbody fusion (PLIF) with a titanium-coated poly-ether-ether-ketone (TCP) cage and PLIF with a three-dimensional porous titanium alloy (PTA) cage.

METHODS

Overall, 63 patients who had undergone 1- or 2-level PLIF since March 2015 were enrolled (median age, 71 years). The first 34 patients underwent PLIF with TCP cages (until June 2017) and the next 29 patients with PTA cages. Fusion status, vertebral endplate cyst formation (cyst sign: grade 0, none; grade 1, focal; and grade 2, diffuse), cage subsidence (grade 0, <1 mm; grade 1, 1-3 mm; and grade 2, >3 mm), and patient-reported quality of life (QOL) outcomes based on the Japanese Orthopaedic Association Back Pain Evaluation Questionnaire (JOABPEQ) were compared at 6 months and 1 year postoperatively between the 2 cage groups.

RESULTS

Cyst sign and cage subsidence grades were significantly lower in the PTA cage group than in the TCP cage group at 6 months postoperatively (cyst sign, p = 0.044; cage subsidence, p = 0.043). In contrast, the fusion rate and surgery effectiveness based on JOABPEQ at both 6 months and 1 year postoperatively were not different between the 2 groups.

CONCLUSIONS

Patient-reported QOL outcomes were similar between the TCP and PTA cage groups until 1 year postoperatively. However, a higher incidence and severity of postoperative vertebral endplate cyst formation in patients with the TCP cage was a noteworthy radiographical finding.

摘要

研究设计

临床病例系列。

目的

比较采用钛涂层聚醚醚酮(TCP)椎间融合器的后路腰椎椎间融合术(PLIF)与采用三维多孔钛合金(PTA)椎间融合器的PLIF在短期(≤1年)的影像学和临床结果。

方法

共纳入自2015年3月起接受1或2节段PLIF手术的63例患者(中位年龄71岁)。前34例患者接受TCP椎间融合器的PLIF手术(至2017年6月),后29例患者接受PTA椎间融合器的PLIF手术。比较两组椎间融合器在术后6个月和1年时的融合状态、椎体终板囊肿形成情况(囊肿征象:0级,无;1级,局灶性;2级,弥漫性)、椎间融合器下沉情况(0级,<1毫米;1级,1 - 3毫米;2级,>3毫米)以及基于日本骨科协会腰痛评估问卷(JOABPEQ)的患者报告的生活质量(QOL)结果。

结果

术后6个月时,PTA椎间融合器组的囊肿征象和椎间融合器下沉分级显著低于TCP椎间融合器组(囊肿征象,p = 0.044;椎间融合器下沉,p = 0.043)。相比之下,两组在术后6个月和1年时基于JOABPEQ的融合率和手术效果并无差异。

结论

在术后1年之前,TCP和PTA椎间融合器组患者报告的QOL结果相似。然而,TCP椎间融合器患者术后椎体终板囊肿形成的发生率和严重程度较高,这是一个值得注意的影像学发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e16f/9344530/b72399b330be/10.1177_2192568220972334-fig1.jpg

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