Tang Weilong, Du Minquan, Zhang Shuang, Jiang Han
The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST), Key Laboratory of Oral Biomedicine Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan, China.
Phytother Res. 2021 May;35(5):2287-2295. doi: 10.1002/ptr.6943. Epub 2020 Nov 17.
Curcumin (diferuloylmethane) is a polyphenol compound extracted from the rhizome of the plant Curcuma longa. It has the feature of being a yellow or orange pigment with a variety of biological properties, including anti-inflammation, antioxidation, anti-tumor, anti-bacteria, anti-fungus, and wound healing. Previous studies have reported the role of curcumin in treating different inflammatory diseases and tumors in vitro and in vivo. Recently, it has been demonstrated that curcumin has therapeutic benefits in oral mucosal diseases, periodontal diseases, and mouth neoplasms. In this review, we will focus on the therapeutic effects of curcumin on oral diseases.
姜黄素(二阿魏酰甲烷)是从植物姜黄的根茎中提取的一种多酚化合物。它具有黄色或橙色色素的特征,具备多种生物学特性,包括抗炎、抗氧化、抗肿瘤、抗菌、抗真菌以及促进伤口愈合。先前的研究报道了姜黄素在体外和体内治疗不同炎症性疾病和肿瘤方面的作用。最近,已证实姜黄素在口腔黏膜疾病、牙周疾病和口腔肿瘤方面具有治疗益处。在本综述中,我们将聚焦于姜黄素对口腔疾病的治疗作用。