接受高效抗逆转录病毒治疗的HIV阳性患者口腔黏膜病变的患病率——一项前瞻性临床研究
Prevalence of oromucosal lesions in HIV positive patients receiving haart-A prospective clinical study.
作者信息
Maloth Saritha, Shrinivas T R, Krishna Pramod B, Nagarathna P J
机构信息
Department of Dentistry, Koppal Institute of Medical Sciences, Koppal, Karnataka, India.
Department of Anesthesiology, Koppal Institute of Medical Sciences, Koppal, Karnataka, India.
出版信息
J Family Med Prim Care. 2020 Sep 30;9(9):4821-4825. doi: 10.4103/jfmpc.jfmpc_881_20. eCollection 2020 Sep.
AIM
To determine the preponderance of oral mucosal lesions and conditions in patients receiving highly active antiretroviral therapy (HAART) for Human Immunodeficiency virus (HIV).
MATERIAL AND METHODS
Patient tested Seropositive for HIV and on HAART therapy were clinically examined to evaluate prevalence of oral lesions.
RESULTS
In the pool of 152 HIV positive patients in the study, age ranged from 7 to 71 years, 67 were males and 85 females. The duration of the HAART medication was 43 months. Oral lesion was present in 51.32% of patients related to infection. Oral lesions seen in descending order of frequency were periodontitis, mucosal hyperpigmentation, acute gingivitis, oral candidiasis, linear gingival erythema, stomatitis, and nonspecific ulcers. Totally, 48.68% of patients had no oral lesions.
CONCLUSION
Majority of the HIV patients on HAART exhibited periodontitis (30.77%), mucosal hyperpigmentation (17.44%), gingivitis (10.77%), anemic stomatitis (11.28%), and other oral lesions accounted to 29.74% which may be attributed to Anti Retro Viral Therapy.
目的
确定接受高效抗逆转录病毒疗法（HAART）治疗人类免疫缺陷病毒（HIV）的患者口腔黏膜病变和病症的主要情况。
材料与方法
对HIV血清检测呈阳性且正在接受HAART治疗的患者进行临床检查，以评估口腔病变的患病率。
结果
在该研究的152例HIV阳性患者中，年龄范围为7至71岁，男性67例，女性85例。HAART药物治疗的持续时间为43个月。51.32%的患者存在与感染相关的口腔病变。按出现频率从高到低排列的口腔病变依次为牙周炎、黏膜色素沉着、急性牙龈炎、口腔念珠菌病、线性牙龈红斑、口腔炎和非特异性溃疡。共有48.68%的患者没有口腔病变。
结论
大多数接受HAART治疗的HIV患者表现出牙周炎（30.77%）、黏膜色素沉着（17.44%）、牙龈炎（10.77%）、贫血性口腔炎（11.28%），其他口腔病变占29.74%，这可能归因于抗逆转录病毒疗法。
Zotero 插件