疟原虫感染红细胞中的谷胱甘肽和过氧化物代谢
Glutathione and peroxide metabolism in malaria-parasitized erythrocytes.
作者信息
Fritsch B, Dieckmann A, Menz B, Hempelmann E, Fritsch K G, Fritsch G, Jung A
机构信息
Physiologisch-chemisches Institut der Universität, Tübingen, Federal Republic of Germany.
出版信息
Parasitol Res. 1987;73(6):515-7. doi: 10.1007/BF00535325.
PMID:3321043
Abstract
The glutathione metabolism of Plasmodium falciparum, P. vinckei and P. berghei has been investigated. Human erythrocytes with low glutathione reductase and synthetase activity are still capable of harbouring P. falciparum. Both enzymes have been demonstrated in Plasmodium spp. Moreover, evidence is given for a selenium-independent glutathione peroxidase in malaria parasites.
摘要
对恶性疟原虫、文氏疟原虫和伯氏疟原虫的谷胱甘肽代谢进行了研究。谷胱甘肽还原酶和合成酶活性较低的人类红细胞仍能够携带恶性疟原虫。在疟原虫属中均已证实存在这两种酶。此外，有证据表明疟原虫中存在一种不依赖硒的谷胱甘肽过氧化物酶。
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