Department of Cardiac Surgery, University Hospital Basel, Basel, Switzerland.
Department of Radiology, University Hospital Basel, Basel, Switzerland.
Interact Cardiovasc Thorac Surg. 2021 Jan 1;32(1):89-96. doi: 10.1093/icvts/ivaa228.
The goal was to evaluate outcomes after conservative or surgical treatment of acute aortic arch dissections.
Between January 2009 and December 2018, patients with a diagnosis of acute aortic dissection were analysed. Aortic arch aortic dissection was defined as a dissection with an isolated entry tear at the aortic arch with no involvement of the ascending aorta.
Aortic arch dissection was diagnosed in 31 patients (age 59 ± 11 years). Surgical intervention was performed in 13 (41.9%) cases. Overall in-hospital mortality was 3% (n = 1), and all deaths occurred in the conservative group (n = 1; 6%), whereas the overall stroke rate was 3% (n = 1), and all strokes occurred in the group treated surgically (n = 1; 8%). Surgical repair was necessary for the following conditions: end-organ malperfusion (n = 9; 69%), impending rupture (n = 3; 23%) and dilatation of the aorta with ongoing pain refractory to medical treatment (n = 1; 8%). Overall survival at the end of the follow-up period was 71%, with 77% in the surgical group and 63% in the conservative group (P = 0.91). Freedom from surgical intervention was 71%, with 82% in the surgical and 63% in the conservative group (P = 0.21), and freedom from a neurological event was 88%, with 89% versus 89% (P = 0.68) in the surgical and conservative groups, respectively.
Aortic arch dissection is a rare pathological condition that is one of the most challenging decision-making entities. Patients manifesting an uneventful course not requiring a surgical intervention during a hospital stay were at a higher risk for aorta-related intervention during the follow-up period. The treatment modality had no impact on survival or on the incidence of a neurological event.
评估急性主动脉弓夹层采用保守或手术治疗的结果。
分析 2009 年 1 月至 2018 年 12 月期间诊断为急性主动脉夹层的患者。主动脉弓夹层定义为孤立的主动脉弓入口撕裂的夹层,不涉及升主动脉。
31 例患者(年龄 59±11 岁)诊断为主动脉弓夹层。13 例(41.9%)患者进行了手术干预。总的院内死亡率为 3%(n=1),且均发生在保守治疗组(n=1;6%),而总的卒中发生率为 3%(n=1),且均发生在手术治疗组(n=1;8%)。手术修复的指征为:终末器官灌注不良(n=9;69%)、即将破裂(n=3;23%)和主动脉扩张伴持续疼痛,药物治疗无效(n=1;8%)。随访期末的总体生存率为 71%,手术组为 77%,保守组为 63%(P=0.91)。免于手术干预的生存率为 71%,手术组为 82%,保守组为 63%(P=0.21),免于神经系统事件的生存率为 88%,手术组为 89%,保守组为 89%(P=0.68)。
主动脉弓夹层是一种罕见的病理情况,是最具挑战性的决策实体之一。在住院期间无手术干预且病情平稳的患者,在随访期间发生主动脉相关干预的风险更高。治疗方式对生存或神经系统事件的发生率没有影响。