Goyal Aditi, Shukla Samarth, Acharya Sourya, Vagha Sunita, Goyal Venkat, Goyal Madhvi
Department of Pathology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India.
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, Maharashtra, India.
J Family Med Prim Care. 2021 Dec;10(12):4376-4382. doi: 10.4103/jfmpc.jfmpc_34_21. Epub 2021 Dec 27.
The novel disease of 2019 by name coronavirus (Covid - 19 or SARS - CoV - 2), was first detected in December of 2019 in the Seafood Market of Huanan in Wuhan region of China. In less than a month it was proclaimed as a pandemic by The World Health Organization (WHO). Now, even after a year, it still remains to be a concern as a jeopardy to the global public health. The inception of Covid-19 has been identified as the third encounter of a highly morbific coronavirus after Severe Acute Respiratory Syndrome (SARS - CoV) and Middle East Respiratory Syndrome (MERS_CoV) causing coronaviruses, in merely two decades. In this review, we illustrate the general features of coronavirus and highlight the pathogenesis of the disease, bringing forth the different theories of disease progression, which may help clinicians and other health professionals to achieve a direction for further research, therapeutic protocols and development of the vaccine for combating SARS - CoV - 2 infection.
这种名为冠状病毒（新冠病毒 - 19 或严重急性呼吸综合征冠状病毒 2）的新型疾病于 2019 年 12 月首次在中国武汉地区的华南海鲜市场被发现。不到一个月，它就被世界卫生组织（WHO）宣布为大流行病。如今，即便在一年之后，它作为对全球公共卫生的一种威胁，仍然令人担忧。新冠病毒 - 19 的出现被认定为是在仅仅二十年时间里，继严重急性呼吸综合征（SARS - CoV）和中东呼吸综合征（MERS - CoV）这两种致病性很强的冠状病毒之后，人类第三次遭遇高致病性冠状病毒。在这篇综述中，我们阐述了冠状病毒的一般特征，并突出了该疾病的发病机制，提出了不同的疾病进展理论，这可能有助于临床医生和其他卫生专业人员为进一步研究、治疗方案以及对抗严重急性呼吸综合征冠状病毒 2 感染的疫苗研发找到方向。
