Emerg Infect Dis. 2021 Jan;27(1):332-4. doi: 10.3201/eid2701.203766. Epub 2020 Nov 23.
The US Food and Drug Administration approved a 6-month regimen of pretomanid, bedaquiline, and linezolid for extensively drug-resistant or multidrug-intolerant tuberculosis after a trial in South Africa demonstrated 90% effectiveness 6 months posttreatment. We report on a patient who completed the regimen using a lower linezolid dose.
美国食品和药物管理局批准了一种为期 6 个月的普托马尼德、贝达喹啉和利奈唑胺治疗方案,用于广泛耐药或耐多药结核病,此前南非的一项试验显示,治疗后 6 个月的有效率为 90%。我们报告了一位使用较低剂量利奈唑胺完成该方案的患者。