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印度的流行性角结膜炎:电子病历驱动的大数据分析报告IV。

Epidemic keratoconjunctivitis in India: electronic medical records-driven big data analytics report IV.

作者信息

Das Anthony Vipin, Basu Sayan

机构信息

Department of eyeSmart EMR & AEye, LV Prasad Eye Institute, Hyderabad, Telangana, India.

The Cornea Institute, LV Prasad Eye Institute, Hyderabad, Telangana, India

出版信息

Br J Ophthalmol. 2022 Mar;106(3):331-335. doi: 10.1136/bjophthalmol-2020-317330. Epub 2020 Nov 23.

Abstract

AIMS

To describe the clinical profile of epidemic keratoconjunctivitis (EKC) in patients presenting to a multitier ophthalmology hospital network in India.

METHODS

This retrospective hospital-based study included 2 408 819 patients presenting between August 2010 and February 2020. Patients with a clinical diagnosis of EKC in at least one eye with a recent onset (≤1 week) were included as cases. The data were collected using the eyeSmart electronic medical record system.

RESULTS

Overall, 21 196 (0.9%) new patients were diagnosed with EKC, of which 19 203 (90.6%) patients reported a recent onset (≤1 week) and were included for analysis. The median age was 32 (IQR: 22-45) years and adults (84.5%) were commonly affected. Most of the patients were male (62.1%) and unilateral (53.4%) affliction was commoner. The most common presenting symptom was redness (63.7%), followed by watering (42.1%). Preauricular lymphadenopathy or tenderness was documented in 1406 (7.3%) cases at presentation. A minority of the eyes had visual impairment worse than 20/200 (7.8%) due to associated ocular comorbidities. The involvement of the cornea was seen in 7338 (38.2%) patients and corneal signs included subepithelial infiltrates (26.3%), epithelial defect (1.4%), corneal oedema (0.9%) and filaments (0.4%). Of the patients who had corneal involvement, 496 (2.6%) patients had a chronic course beyond 1 month of which 105 (0.5%) had a course beyond 1 year.

CONCLUSION

EKC is a self-limiting condition that is commonly unilateral and predominantly affects males. About one-third of the patients have corneal involvement which rarely has a chronic course.

摘要

目的

描述在印度一家多层眼科医院网络就诊的流行性角结膜炎(EKC)患者的临床特征。

方法

这项基于医院的回顾性研究纳入了2010年8月至2020年2月期间就诊的2408819例患者。至少一只眼睛临床诊断为近期发病(≤1周)的EKC患者被纳入病例组。数据通过eyeSmart电子病历系统收集。

结果

总体而言,21196例(0.9%)新患者被诊断为EKC,其中19203例(90.6%)患者报告近期发病(≤1周)并被纳入分析。中位年龄为32岁(四分位间距:22 - 45岁),成人(84.5%)受影响较为常见。大多数患者为男性(62.1%),单侧患病(53.4%)更为常见。最常见的症状是眼红(63.7%),其次是流泪(42.1%)。就诊时1406例(7.3%)病例记录有耳前淋巴结肿大或压痛。少数眼睛因相关眼部合并症视力损害超过20/200(比例为7.8%)。7338例(38.2%)患者出现角膜受累,角膜体征包括上皮下浸润(26.3%)、上皮缺损(1.4%)、角膜水肿(0.9%)和丝状角膜炎(0.4%)。在角膜受累的患者中,496例(2.6%)病程超过1个月,其中105例(0.5%)病程超过1年。

结论

EKC是一种自限性疾病,通常为单侧发病,主要影响男性。约三分之一的患者角膜受累,很少有慢性病程。

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