Li Shuang, Wang Jing-Jing, Li Hong-Yang, Wang Wei, Tian Meng, Lang Xu-Qiang, Wang Kang
Department of Ophthalmology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, P.R. China.
Exp Ther Med. 2021 Jan;21(1):19. doi: 10.3892/etm.2020.9451. Epub 2020 Nov 5.
The present study aimed to compare the imaging performance of two ultra-wide-field fluorescein angiography imaging systems, namely the OptosOptomap 200Tx (Optos 200Tx) and the Heidelberg Spectralis (Spectralis). A total of 18 patients (36 eyes) underwent angiography using the two systems at the Department of Ophthalmology, Beijing Friendship Hospital (Beijing, China) between January and June 2017. The images were obtained as a single shot centered on the macula. The total area and area within each of four visualized quadrants were calculated and compared. The averages of the total and individual quadrant area captured by the Optos 200Tx were all larger than those obtained with the Spectralis (P<0.05). For pair-wise comparison, the circular area centered on the macula (radius of 10 and 15 mm) was displayed: Optos 200Tx 10 mm (295.57 mm) < Spectralis (520.11 mm) < Optos 200Tx 15 mm (596.45 mm) < Optos 200Tx (804.36 mm) (P<0.01). The differences of each of the four quadrant areas were statistically significant between the two systems (P<0.05). The mean size of the areas was in the following order: Inferior < temporal < superior < nasal for the Optos 200Tx, and inferior < temporal < nasal < superior for the Spectralis. Further comparison of the four-quadrant area indicated that the inferior quadrant of the Optos 200Tx was smaller than the other three quadrants (P<0.01) and the inferior quadrant of the Spectralis was smaller than the superior quadrant (P<0.01). The total retinal area and the retinal area of each quadrant captured by the Optos 200Tx were larger than those captured with the Spectralis. The total retinal area captured with the Optos 200Tx was able to cover the mid-peripheral area and part of the far-peripheral area of the retina, whereas the Spectralis only covered the mid-peripheral area.
本研究旨在比较两种超广角荧光素血管造影成像系统的成像性能，即Optos Optomap 200Tx（Optos 200Tx）和海德堡Spectralis（Spectralis）。2017年1月至6月期间，共有18例患者（36只眼）在北京友谊医院眼科使用这两种系统进行血管造影。图像以黄斑为中心单次拍摄获得。计算并比较了四个可见象限的总面积和每个象限内的面积。Optos 200Tx捕获的总面积和各个象限面积的平均值均大于Spectralis获得的平均值（P<0.05）。进行两两比较时，显示了以黄斑为中心的圆形区域（半径为10和15毫米）：Optos 200Tx 10毫米（295.57平方毫米）<Spectralis（520.11平方毫米）<Optos 200Tx 15毫米（596.45平方毫米）<Optos 200Tx（804.36平方毫米）（P<0.01）。两种系统之间四个象限面积的差异均具有统计学意义（P<0.05）。面积的平均大小顺序如下：Optos 200Tx为下方<颞侧<上方<鼻侧，Spectralis为下方<颞侧<鼻侧<上方。四个象限面积的进一步比较表明，Optos 200Tx的下方象限小于其他三个象限（P<0.01），Spectralis的下方象限小于上方象限（P<0.01）。Optos 200Tx捕获的视网膜总面积和每个象限的视网膜面积大于Spectralis捕获的面积。Optos 200Tx捕获的视网膜总面积能够覆盖视网膜的中周部区域和部分远周部区域，而Spectralis仅覆盖中周部区域。
