Faculty of Sciences, Ibn Tofaïl University, Kenitra, Morocco.
Royal Institute of Managers Training, Sale, Morocco.
Pan Afr Med J. 2020 Aug 31;36:381. doi: 10.11604/pamj.2020.36.381.24870. eCollection 2020.
this work aims to bring out the epidemiological characteristics of extrapulmonary tuberculosis (EPTB) in the province of Larache (Morocco) and to investigate the effect of gender and age on its localization and treatment outcome.
it consists in a retrospective study based on 2962 cases of EPTB, reported during the period 2000 to 2012.
the mean age was 31.74 ± 18.83 years, with a median age of 26. Males are more affected by this form of tuberculosis, with a male to female sex-ratio of 1,15. The EPTB affects particularly the young population whose age is between 15 and 34 years. The pleural and lymph node localizations are the most common with 45% and 28% respectively. The statistical analysis reveals that younger patients are preferentially affected by lymph node tuberculosis whereas oldest ones are more likely to suffer from urogenital and pericardial tuberculosis. Regarding the treatment outcome, we demonstrated that age is significantly associated with the treatment outcome and that deaths occur preferentially in the oldest patients. Finally, we found out a significant association between males and pleural ETB localization, and between females and lymph node and peritoneo-itestinal ETB localizations.
special attention must be paid to the mentioned most vulnerable categories of EPTB patients.
本研究旨在揭示摩洛哥拉腊什省（Larache）肺外结核（EPTB）的流行病学特征，并探讨性别和年龄对其定位和治疗结果的影响。
这是一项基于 2000 年至 2012 年期间报告的 2962 例 EPTB 病例的回顾性研究。
平均年龄为 31.74 ± 18.83 岁，中位数为 26 岁。男性更容易受到这种形式的结核病的影响，男性与女性的性别比为 1.15。EPTB 特别影响年轻人，年龄在 15 至 34 岁之间。胸膜和淋巴结定位是最常见的，分别占 45%和 28%。统计分析表明，年轻患者更容易患淋巴结结核，而最年长的患者更容易患泌尿生殖和心包结核。关于治疗结果，我们表明年龄与治疗结果显著相关，且死亡主要发生在最年长的患者中。最后，我们发现男性与胸膜 EPTB 定位之间存在显著关联，而女性与淋巴结和腹膜 EPTB 定位之间存在显著关联。
必须特别关注上述 EPTB 患者中最脆弱的类别。
