Higher Academy for Strategic and Security Studies, Khartoum, Sudan.
Medical Microbiology Department, Faculty of Medical Laboratory Sciences, University of Khartoum, Khartoum, Sudan.
BMC Pulm Med. 2024 Jan 23;24(1):51. doi: 10.1186/s12890-024-02865-6.
Every year, 10 million people fall ill with tuberculosis (TB). Despite being a preventable and curable disease, 1.5 million people die from TB each year -making it the world's top infectious disease. TB is the leading cause of death of people with HIV and also a major contributor to antimicrobial resistance. Its presumed that TB was the cause of 1% of the total deaths among inpatients in Sudan in 2017. The current study is aimed to provide pooled prevalence of Mycobacterium tuberculosis among Sudanese as well as to determine any socio-cultural risk factors associated. A systematic review of the literature was conducted and regulated in accordance with the PRISMA Statement. After abstract and full text screening only twenty-six articles met our inclusion criteria and passed the quality assessment procedure. Pulmonary tuberculosis prevalence was assessed in sixteen included studies among participants from Khartoum, Gezira, Kassala, Blue Nile, River Nile, White Nile, Gadarif, Red sea, North Kordofan, Northern State, Sennar and West Darfur States, representing a total sample size of 11,253 participants of suspected individuals such as febrile outpatients, TB patients' contacts and other groups such as HIV/AIDS patients, hemodialysis patients, School adolescents as well as pregnant women. The pooled prevalence was 30.72% [CI: 30.64, 30.81]. Moreover, Khartoum State recorded the highest pooled prevalence as 41.86% [CI: 14.69, 69.02] based on a total sample size of 2,737 participants. Furthermore, male gender and rural residence were found to be significantly associated with TB infection. Further research with larger sample sizes targeting prevalence and risk factors of TB among Sudanese population is needed to be conducted.
每年有 1000 万人感染结核病（TB）。尽管结核病是一种可预防和可治愈的疾病，但每年仍有 150 万人死于结核病——使其成为全球头号传染病。结核病是导致 HIV 感染者死亡的主要原因，也是导致抗微生物药物耐药性的主要原因。据推测，2017 年苏丹住院患者总死亡人数中，结核病占 1%。本研究旨在提供苏丹人群中结核分枝杆菌的患病率，并确定与结核病相关的任何社会文化危险因素。系统检索文献并按照 PRISMA 声明进行规范。经过摘要和全文筛选，只有 26 篇文章符合纳入标准并通过了质量评估程序。在包括来自喀土穆、杰济拉、卡萨拉、青尼罗河、尼罗河、白尼罗河、加达里夫、红海、北科尔多凡、北方州、森纳尔和西达尔富尔州的参与者的 16 项纳入研究中评估了肺结核患病率，总样本量为 11253 名疑似发热门诊患者、结核病患者接触者和其他群体如 HIV/AIDS 患者、血液透析患者、学校青少年以及孕妇。汇总患病率为 30.72%[95%CI:30.64,30.81]。此外，根据总样本量为 2737 名参与者的研究，喀土穆州的患病率最高，为 41.86%[95%CI:14.69,69.02]。此外，男性和农村居住与结核病感染显著相关。需要进一步开展研究，以确定苏丹人群中结核病的患病率和危险因素。
