Yorulmaz Ahu, Artuz Ferda
Department of Dermatology, Ankara Numune Research and Education Hospital, Ankara, Turkey.
Postepy Dermatol Alergol. 2017 Feb;34(1):28-35. doi: 10.5114/ada.2017.65618. Epub 2017 Feb 7.
Dermoscopy is a non-invasive imaging method that enables the evaluation of pigmented and non-pigmented skin lesions. More recently, dermoscopy has been recognized as an effective tool in the diagnosis of nail diseases.
To evaluate the dermoscopic features of nail psoriasis and to assess the relationship between these features and disease severity.
A total of 67 patients with clinically evident nail psoriasis (14 women, 53 men) were prospectively enrolled. Following a thorough clinical examination, patients were graded according to the Nail Psoriasis Severity Index and physician's global assessment score. A dermoscopic examination of all fingernails and toenails was performed using a videodermatoscope. Mann-Whitney and χ tests were used for statistical analysis, with a significance threshold of < 0.05.
The most frequently observed dermoscopic features were splinter haemorrhage (73.1%), pitting (58.2%), distal onycholysis (55.2%), dilated hyponychial capillaries (35.8%) and the pseudo-fiber sign (34.3%). The pseudo-fiber sign, dilated hyponychial capillaries, nail plate thickening and crumbling, subungual hyperkeratosis, transverse grooves, trachyonychia, pitting and salmon patches were positively associated with disease severity.
The pseudo-fiber sign described in this study appears to be a novel dermoscopic feature of nail psoriasis. We have demonstrated positive associations between a number of dermoscopic manifestations and disease severity. Further studies are required to support the present findings.
皮肤镜检查是一种非侵入性成像方法,可用于评估色素性和非色素性皮肤病变。最近,皮肤镜检查已被公认为诊断指甲疾病的有效工具。
评估指甲银屑病的皮肤镜特征,并评估这些特征与疾病严重程度之间的关系。
前瞻性纳入67例临床诊断为指甲银屑病的患者(14例女性,53例男性)。经过全面的临床检查后,根据指甲银屑病严重程度指数和医生的整体评估评分对患者进行分级。使用视频皮肤镜对所有手指甲和脚趾甲进行皮肤镜检查。采用Mann-Whitney检验和χ检验进行统计分析,显著性阈值为<0.05。
最常观察到的皮肤镜特征为裂片形出血(73.1%)、甲凹点(58.2%)、远端甲剥离(55.2%)、甲下毛细血管扩张(35.8%)和假纤维征(34.3%)。假纤维征、甲下毛细血管扩张、甲板增厚和碎裂、甲下角化过度、横向沟、粗糙甲、甲凹点和鲑鱼斑与疾病严重程度呈正相关。
本研究中描述的假纤维征似乎是指甲银屑病一种新的皮肤镜特征。我们已经证明了一些皮肤镜表现与疾病严重程度之间的正相关。需要进一步的研究来支持目前的发现。