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模拟供体筛查策略以降低严重急性呼吸综合征冠状病毒2通过粪便微生物群移植传播的风险

Modeling Donor Screening Strategies to Reduce the Risk of Severe Acute Respiratory Syndrome Coronavirus 2 Transmission via Fecal Microbiota Transplantation.

作者信息

Olesen Scott W, Zaman Amanda, Osman Majdi, Ramakrishna Bharat

机构信息

OpenBiome, Cambridge, Massachusetts, USA.

出版信息

Open Forum Infect Dis. 2020 Oct 19;7(11):ofaa499. doi: 10.1093/ofid/ofaa499. eCollection 2020 Nov.

Abstract

The potential for transmission of severe acute respiratory syndrome coronavirus 2 shed in stool via fecal microbiota transplantation is not yet known, and the effectiveness of various testing strategies to prevent fecal microbiota transplantation-based transmission has also not yet been quantified. In this study, we use a mathematical model to simulate the utility of different testing strategies.

摘要

通过粪便微生物群移植传播严重急性呼吸综合征冠状病毒2的可能性尚不清楚,并且各种检测策略预防基于粪便微生物群移植传播的有效性也尚未量化。在本研究中,我们使用数学模型来模拟不同检测策略的效用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2f3a/7672474/26cbc9a9a937/ofaa499_fig1.jpg

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