Lian Jie, Xu Qiang, Wang Yipeng, Meng Fanda
College of Criminal Investigation, People's Public Security University of China, Beijing, China.
Institute of Basic Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, Shandong, China.
Front Chem. 2020 Nov 10;8:593291. doi: 10.3389/fchem.2020.593291. eCollection 2020.
Forensic chemistry deals with the analysis of various types of physical evidences related to crime, corresponding to the detection of target substances or elements in complex matrices. There is a vital need for highly selective, rapid, and sensitive biosensing technologies in heavy metal ions analysis especially those from living persons, autopsy, food, water, soil, and other identified substances at very preliminary stages. Fluorescent materials-based method for heavy metal ions detection is one of the most important analytical methods, resulting in the ability to measure analytes in complex matrices with unsurpassed selectivity and sensitivity. In this mini review, different fluorescent materials-based analytical methods aiming at several heavy metal ions detection are exclusively reviewed through a comprehensive literature survey. In addition, current challenges to achieve integrated evidence analysis process are briefly discussed to provide an outlook for heavy metal ions detection based on fluorescent analytical methods in the forensic chemistry field.
法医化学涉及对与犯罪相关的各类物证进行分析,这相当于在复杂基质中检测目标物质或元素。在重金属离子分析中,尤其是对来自活体、尸体解剖、食物、水、土壤及其他在极早期阶段已识别物质中的重金属离子分析而言,迫切需要高选择性、快速且灵敏的生物传感技术。基于荧光材料的重金属离子检测方法是最重要的分析方法之一,它能够以无与伦比的选择性和灵敏度在复杂基质中测量分析物。在本综述中,通过全面的文献调研专门综述了针对几种重金属离子检测的不同基于荧光材料的分析方法。此外,还简要讨论了实现综合证据分析过程目前面临的挑战,以期为法医化学领域基于荧光分析方法的重金属离子检测提供展望。