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新冠疫情时代的上消化道肿瘤管理:感染风险、内镜作用的适应性转变以及潜在的治疗方案改变。

Upper Gastrointestinal Cancer Management in the COVID-19 Era: Risk of Infection, Adapted Role of Endoscopy, and Potential Treatment Algorithm Alterations.

机构信息

1st Department of Surgery, Laikon General Hospital, National and Kapodistrian University of Athens, Agiou Thoma 17 Street, 11527, Athens, Greece.

First Propaedeutic Department of Surgery, Hippocration General Hospital, National and Kapodistrian University of Athens, Athens, Greece.

出版信息

J Gastrointest Cancer. 2021 Jun;52(2):407-413. doi: 10.1007/s12029-020-00557-y. Epub 2020 Nov 26.

Abstract

INTRODUCTION

The safety of upper gastrointestinal cancer patients in the SARS-CoV-2 outbreak is extremely important and most surgeons need to establish a contingency management.

AIM

In this study, we present the surgical outlines of patients suffering from upper gastrointestinal cancers.

MATERIALS AND METHODS

Data were obtained from PubMed, Cochrane Database of Controlled Trials, and SCOPUS of reports up to September 2020.

RESULTS

The COVID-19 outbreak makes surgical procedures extremely difficult to be performed. The most common criteria to prioritize patients for surgical treatment are stage, tumor biology, presence of tumor-related symptoms, the risk of tumor to become non-resectable, and time interval from neoadjuvant therapy. The multidisciplinary teams can help assigning a priority level to each clinical case.

CONCLUSION

We have to continue providing treatment to oncologic patients in the face of COVID-19 uncertainty, with higher caution and responsibility in order to develop a safer and more effective personalized treatment plan.

摘要

简介

在 SARS-CoV-2 爆发期间,上消化道癌症患者的安全极其重要,大多数外科医生需要制定应急管理方案。

目的

本研究介绍了上消化道癌症患者的手术概况。

材料和方法

数据来自截至 2020 年 9 月的 PubMed、Cochrane 对照试验数据库和 SCOPUS 报告。

结果

COVID-19 疫情使得手术操作极其困难。优先考虑手术治疗的患者最常见的标准是分期、肿瘤生物学、肿瘤相关症状的存在、肿瘤变为不可切除的风险,以及新辅助治疗的时间间隔。多学科团队可以帮助为每个临床病例分配优先级。

结论

我们必须继续为面对 COVID-19 不确定性的肿瘤患者提供治疗,以更高的谨慎和责任感制定更安全、更有效的个体化治疗计划。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/355f/7690947/6334fb367ebf/12029_2020_557_Fig1_HTML.jpg

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