Omidifar Navid, Pazoki Nasrin, Shokripour Mansoureh, Fattahi Mohammad Reza, Safarpour Ali Reza, Fallahzadeh Abarghooee Ebrahim, Nikmanesh Nika, Shamsdin Seyedeh Azra, Akrami Hassan, Saghi Seyyed Amirreza, Nikmanesh Yousef
Biotechnology Research Center and Department of Pathology, Medical School, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Genetics, Faculty of Biological Sciences, North Tehran Branch, Islamic Azad University, Tehran, Iran.
Middle East J Dig Dis. 2024 Jan;16(1):12-22. doi: 10.34172/mejdd.2024.363. Epub 2024 Jan 31.
Coronavirus is a new virus that has affected human life on a large scale; it has infected millions of people and killed hundreds of thousands of people. In contrast, among cancers, stomach neoplasia is the most common cancer of the upper gastrointestinal (UGI) tract. COVID-19 disease has disrupted the optimal management of patients with cancer. Metastasis, deterioration of the patient's nutritional status, UGI bleeding, and increased surgical complications are all consequences of delayed treatment of patients with gastric cancer. However, there is still insufficient evidence on the immunogenicity of the vaccine and the protection provided by coronavirus vaccines in patients with cancer, especially those with immunodeficiency or those who are treated for certain types of cancers. Also, as part of the prevention and control of COVID-19 disease, nutritional support for patients with gastrointestinal cancer is particularly important, and the psychological and physiological limitations caused by the disease duration are hurting the well-being of patients. Therefore, the assessment of the impact of the coronavirus on cancer should be treated as an important issue, and healthcare professionals should be prepared to deal with the long-term effects of the coronavirus disease.
冠状病毒是一种新型病毒，已在很大程度上影响了人类生活；它感染了数百万人，并导致数十万人死亡。相比之下，在癌症中，胃肿瘤是上消化道（UGI）最常见的癌症。COVID-19疾病扰乱了癌症患者的最佳治疗。转移、患者营养状况恶化、UGI出血以及手术并发症增加都是胃癌患者治疗延迟的后果。然而，关于疫苗的免疫原性以及冠状病毒疫苗对癌症患者，尤其是免疫缺陷患者或接受某些类型癌症治疗的患者所提供的保护，仍然证据不足。此外，作为COVID-19疾病防控的一部分，对胃肠癌患者的营养支持尤为重要，而病程所造成的心理和生理限制正在损害患者的健康。因此，评估冠状病毒对癌症的影响应被视为一个重要问题，医疗保健专业人员应做好应对冠状病毒疾病长期影响的准备。
