超长距离马拉松赛后血清维生素 D 代谢物水平的升高：一项双盲随机对照试验。
Ultra-Marathon-Induced Increase in Serum Levels of Vitamin D Metabolites: A Double-Blind Randomized Controlled Trial.
机构信息
Department of Gymnastics and Dance, Gdansk University of Physical Education and Sport, 80-336 Gdansk, Poland.
Institute of Physical Education, Kazimierz Wielki University, 85-064 Bydgoszcz, Poland.
出版信息
Nutrients. 2020 Nov 25;12(12):3629. doi: 10.3390/nu12123629.
PURPOSE
While an increasing number of studies demonstrate the importance of vitamin D for athletic performance, the effects of any type of exercise on vitamin D metabolism are poorly characterized. We aimed to identify the responses of some vitamin D metabolites to ultra-marathon runs.
METHODS
A repeated-measures design was implemented, in which 27 amateur runners were assigned into two groups: those who received a single dose of vitamin D (150,000 IU) 24 h before the start of the marathon ( = 13) and those ( = 14) who received a placebo. Blood samples were collected 24 h before, immediately after, and 24 h after the run.
RESULTS
In both groups of runners, serum 25(OH)D, 24,25(OH)D, and 3--25(OH)D levels significantly increased by 83%, 63%, and 182% after the ultra-marathon, respectively. The increase was most pronounced in the vitamin D group. Body mass and fat mass significantly decreased after the run in both groups.
CONCLUSIONS
Ultra-marathon induces the mobilization of vitamin D into the blood. Furthermore, the 24,25(OH)D and 3--25(OH)D increases imply that the exercise stimulates vitamin D metabolism.
目的
虽然越来越多的研究表明维生素 D 对运动表现很重要，但运动对维生素 D 代谢的任何影响都知之甚少。我们旨在确定一些维生素 D 代谢物对超长马拉松跑步的反应。
方法
采用重复测量设计，将 27 名业余跑步者分为两组：一组在马拉松开始前 24 小时（= 13）接受单次维生素 D（150000IU）剂量，另一组（= 14）接受安慰剂。在跑步前 24 小时、跑步后立即和跑步后 24 小时采集血样。
结果
在两组跑步者中，血清 25（OH）D、24、25（OH）D 和 3--25（OH）D 水平在超长马拉松后分别显著增加了 83%、63%和 182%。维生素 D 组的增幅最大。两组跑步者在跑步后体重和体脂均显著下降。
结论
超长马拉松会促使维生素 D 进入血液。此外，24、25（OH）D 和 3--25（OH）D 的增加表明运动刺激了维生素 D 代谢。
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