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柄周围假体周围骨折固定中对接钉概念的生物力学评估全膝关节置换术。

Biomechanical evaluation of the docking nail concept in periprosthetic fracture fixation around a stemmed total knee arthroplasty.

机构信息

AO Research Institute Davos, Switzerland; Department of Trauma, Hand and Reconstructive Surgery, University Hospital Jena, Germany.

University Hospital Basel, Switzerland.

出版信息

J Biomech. 2021 Jan 22;115:110109. doi: 10.1016/j.jbiomech.2020.110109. Epub 2020 Nov 18.

Abstract

Intramedullary femoral nails provide an ideal mechanical axis for periprosthetic fracture fixation. Slotted nails allow a connection to a total knee arthroplasty (TKA) stem. This study aims to compare implant and construct stiffness, interfragmentary movement and cycles to failure between an antegrade slotted femoral nail construct docked to a TKA stem and a distal femoral locking plate in a human periprosthetic femoral fracture model. In eight pairs of fresh-frozen human femora with stalked TKA, a 10 mm transverse osteotomy gap was set simulating a Rorabeck type II, Su type I fracture. The femora were pairwise instrumented with either an antegrade slotted nail coupled to the prosthesis stem, or a locking plate. Cyclic testing with a progressively increasing physiologic loading profile was performed at 2 Hz until catastrophic construct failure. Relative movement at the osteotomy site was monitored by means of optical motion tracking. In addition, four-point bending implant stiffness, torsional implant stiffness and frictional fit of the stem-nail connection were investigated via separate non-destructive tests. Intramedullary nails exhibited significantly higher four-point bending and significantly lower torsional implant stiffness than plates, P < 0.01. Increasing difference between nail and stem diameters decreased frictional fit at the stem-nail junction. Nail constructs provided significantly higher initial axial bending stiffness and cycles to failure (200 ± 83 N/mm; 16'871 ± 5'227) compared to plate constructs (93 ± 35 N/mm; 7'562 ± 1'064), P = 0.01. Relative axial translation at osteotomy level after 2'500 cycles was significantly smaller for nail fixation (0.14 ± 0.11 mm) compared with plate fixation (0.99 ± 0.20 mm), P < 0.01. From a biomechanical perspective, the docking nail concept offers higher initial and secondary stability under dynamic axial loading versus plating in TKA periprosthetic fracture fixation.

摘要

髓内股骨钉为假体周围骨折固定提供了理想的力学轴。有槽钉允许与全膝关节置换(TKA)柄连接。本研究旨在比较顺行开槽股骨钉固定器与 TKA 柄对接的假体和结构刚度、骨折间活动度和失效循环,以及在人工假体周围股骨骨折模型中使用远端股骨锁定板的情况。在 8 对带有 TKA 柄的新鲜冷冻人股骨中,设置了 10mm 横断骨切开间隙,模拟 Rorabeck Ⅱ型、Su Ⅰ型骨折。将股骨成对地用顺行开槽钉与假体柄连接,或用锁定板进行仪器固定。在 2Hz 下以逐渐增加的生理负荷曲线进行循环测试,直至发生灾难性结构失效。通过光学运动跟踪监测骨切开部位的相对运动。此外,通过单独的非破坏性测试研究了四点弯曲植入物刚度、扭转植入物刚度和柄钉连接的摩擦配合。髓内钉的四点弯曲和扭转植入物刚度明显高于钢板,P<0.01。钉和柄直径之间的差异增大,会降低柄钉连接处的摩擦配合。与钢板固定器(93±35 N/mm;7'562±1'064)相比,钉固定器提供了更高的初始轴向弯曲刚度和失效循环(200±83 N/mm;16'871±5'227),P=0.01。在 2'500 次循环后,骨切开处的相对轴向平移,钉固定明显小于钢板固定(0.14±0.11mm 比 0.99±0.20mm),P<0.01。从生物力学角度来看,在 TKA 假体周围骨折固定中,与钢板固定相比,对接钉概念在动态轴向加载下提供了更高的初始和次要稳定性。

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