Helmholtz-Institute for Biomedical Engineering, RWTH Aachen University, Pauwelsstr. 20, 52074, Aachen, Germany.
Sci Rep. 2020 Nov 30;10(1):20859. doi: 10.1038/s41598-020-77479-z.
The identification of femoral landmarks is a common procedure in multiple academic fields. Femoral bone coordinate systems are used particularly in orthopedics and biomechanics, and are defined by landmarks, axes and planes. A fully automatic detection overcomes the drawbacks of a labor-intensive manual identification. In this paper, a new automatic atlas- and a priori knowledge-based approach that processes femoral surface models, called the A&A method, was evaluated. The A&A method is divided in two stages. Firstly, a single atlas-based registration maps landmarks and areas from a template surface to the subject. In the second stage, landmarks, axes and planes that are used to construct several femoral bone coordinate systems are refined using a priori knowledge. Three common femoral coordinate systems are defined by the landmarks detected. The A&A method proved to be very robust against a variation of the spatial alignment of the surface models. The results of the A&A method and a manual identification were compared. No significant rotational differences existed for the bone coordinate system recommended by the International Society of Biomechanics. Minor significant differences of maximally 0.5° were observed for the two other coordinate systems. This might be clinically irrelevant, depending on the context of use and should, therefore, be evaluated by the potential user regarding the specific application. The entire source code of the A&A method and the data used in the study is open source and can be accessed via https://github.com/RWTHmediTEC/FemoralCoordinateSystem .
在多个学术领域中,识别股骨标志是一项常见的操作。股骨坐标系尤其在骨科和生物力学中得到广泛应用,其定义由标志点、轴和平面组成。全自动检测方法克服了人工手动识别的繁琐。本文评估了一种新的基于图谱和先验知识的全自动股骨表面模型检测方法,称为 A&A 方法。A&A 方法分为两个阶段。首先,基于单个图谱的注册将模板表面上的标志点和区域映射到主体上。在第二阶段,使用先验知识对用于构建多个股骨坐标系的标志点、轴和平面进行细化。通过检测到的标志点定义了三个常见的股骨坐标系。A&A 方法在表面模型的空间对齐发生变化时表现出很强的稳健性。比较了 A&A 方法和手动识别的结果。对于国际生物力学学会推荐的骨坐标系,没有发现明显的旋转差异。对于另外两个坐标系,观察到的最大差异为 0.5°,这可能在临床上并不重要,具体取决于使用的上下文,因此,潜在用户应根据具体应用对其进行评估。A&A 方法的整个源代码和研究中使用的数据都是开源的,可以通过 https://github.com/RWTHmediTEC/FemoralCoordinateSystem 访问。