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成人患者肠内管内镜管理 - 第 1 部分:定义和适应证。欧洲胃肠道内镜学会(ESGE)指南。

Endoscopic management of enteral tubes in adult patients - Part 1: Definitions and indications. European Society of Gastrointestinal Endoscopy (ESGE) Guideline.

机构信息

Department of Gastroenterology, Hepatopancreatology and Digestive Oncology, CUB Hôpital Erasme, Université Libre de Bruxelles, Brussels, Belgium.

Royal Free Unit for Endoscopy and Centre for Gastroenterology, UCL Institute for Liver and Digestive Health, The Royal Free Hospital, London, United Kingdom.

出版信息

Endoscopy. 2021 Jan;53(1):81-92. doi: 10.1055/a-1303-7449. Epub 2020 Dec 1.

Abstract

ESGE recommends considering the following indications for enteral tube insertion: (i) clinical conditions that make oral intake impossible (neurological conditions, obstructive causes); (ii) acute and/or chronic diseases that result in a catabolic state where oral intake becomes insufficient; and (iii) chronic small-bowel obstruction requiring a decompression gastrostomy.Strong recommendation, low quality evidence.ESGE recommends the use of temporary feeding tubes placed through a natural orifice (either nostril) in patients expected to require enteral nutrition (EN) for less than 4 weeks. If it is anticipated that EN will be required for more than 4 weeks, percutaneous access should be considered, depending on the clinical setting.Strong recommendation, low quality evidence.ESGE recommends the gastric route as the primary option in patients in need of EN support. Only in patients with altered/unfavorable gastric anatomy (e. g. after previous surgery), impaired gastric emptying, intolerance to gastric feeding, or with a high risk of aspiration, should the jejunal route be chosen.Strong recommendation, moderate quality evidence.ESGE suggests that recent gastrointestinal (GI) bleeding due to peptic ulcer disease with risk of rebleeding should be considered to be a relative contraindication to percutaneous enteral access procedures, as should hemodynamic or respiratory instability.Weak recommendation, low quality evidence.ESGE suggests that the presence of ascites and ventriculoperitoneal shunts should be considered to be additional risk factors for infection and, therefore, further preventive precautions must be taken in these cases.Weak recommendation, low quality evidence.ESGE recommends that percutaneous tube placement (percutaneous endoscopic gastrostomy [PEG], percutaneous endoscopic gastrostomy with jejunal extension [PEG-J], or direct percutaneous endoscopic jejunostomy [D-PEJ]) should be considered to be a procedure with high hemorrhagic risk, and that in order to reduce this risk, specific guidelines for antiplatelet or anticoagulant use should be followed strictly.Strong recommendation, low quality evidence.ESGE recommends refraining from PEG placement in patients with advanced dementia.Strong recommendation, low quality evidence.ESGE recommends refraining from PEG placement in patients with a life expectancy shorter than 30 days.Strong recommendation, low quality evidence*.

摘要

ESGE 建议考虑以下肠内管插入的适应证:(i)使经口摄入不可能的临床情况(神经状况,梗阻性原因);(ii)导致分解代谢状态的急性和/或慢性疾病,经口摄入变得不足;和(iii)需要减压胃造口术的慢性小肠梗阻。强烈推荐,低质量证据。ESGE 建议在预计需要肠内营养(EN)少于 4 周的患者中使用通过自然孔道(任一侧鼻孔)放置的临时喂养管。如果预计需要超过 4 周的 EN,则应根据临床情况考虑经皮途径。强烈推荐,低质量证据。ESGE 建议在需要 EN 支持的患者中,胃途径是首选。只有在胃解剖结构改变/不适合(例如,先前手术后)、胃排空受损、不能耐受胃喂养或有高吸入风险的患者中,才应选择空肠途径。强烈推荐,中等质量证据。ESGE 建议,由于消化性溃疡病导致最近出现胃肠道(GI)出血且有再出血风险,应被认为是经皮肠内进入术的相对禁忌证,此外还包括血流动力学或呼吸不稳定。弱推荐,低质量证据。ESGE 建议腹水和脑室-腹膜分流术的存在应被视为感染的其他危险因素,因此在这些情况下必须采取进一步的预防措施。弱推荐,低质量证据。ESGE 建议经皮管放置(经皮内镜胃造口术 [PEG]、经皮内镜胃造口术加空肠延长术 [PEG-J] 或直接经皮内镜空肠造口术 [D-PEJ])应被视为具有高出血风险的程序,为了降低这种风险,应严格遵循针对抗血小板或抗凝药物使用的具体指南。强烈推荐,低质量证据。ESGE 建议避免在有晚期痴呆症的患者中进行 PEG 放置。强烈推荐,低质量证据。ESGE 建议避免在预期寿命短于 30 天的患者中进行 PEG 放置。强烈推荐,低质量证据*。

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