Conti Eugenia, Sgandurra Giuseppina, De Nicola Giacomo, Biagioni Tommaso, Boldrini Silvia, Bonaventura Eleonora, Buchignani Bianca, Della Vecchia Stefania, Falcone Francesca, Fedi Caterina, Gazzillo Marisa, Marinella Gemma, Mazzullo Cristina, Micomonaco Jessica, Pantalone Gloria, Salvati Andrea, Sesso Gianluca, Simonelli Valerio, Tolomei Greta, Troiano Irene, Cioni Giovanni, Masi Gabriele, Muratori Filippo, Milone Annarita, Battini Roberta
IRCCS Fondazione Stella Maris, 56128 Pisa, Italy.
Department of Clinical ad Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Brain Sci. 2020 Nov 27;10(12):918. doi: 10.3390/brainsci10120918.
On 11 March 2020, a national lockdown was imposed by the Italian government to contain the spread of COVID19 disease. This is an observational longitudinal study conducted at Fondazione Stella Maris (FSM), Italy to investigate lockdown-related emotional and behavioural changes in paediatric neuropsychiatric population. Families having children (1.5-18 years) with neuropsychiatric disorders referred to FSM have been contacted and proposed to fulfil two online questionnaires (General questionnaire and Child Behaviour Check List (CBCL)) to (i) compare (paired two-sample -tests) the CBCL scores during lockdown with previous ones, and (ii) investigate the influence (multiple linear regression models) of variables such as age, diagnosis grouping (neurological, neurodevelopmental, emotional, and behavioural disorders) and financial hardship. One hundred and forty-one parents fulfilled the questionnaires. Anxiety and somatic problems increased in 1.5-5 years subpopulation, while obsessive-compulsive, post-traumatic and thought problems increased in 6-18 years subpopulation. In the regression models, younger age in the 1.5-5 years subpopulation resulted as "protective" while financial hardship experienced by families during lockdown was related to psychiatric symptoms increasing in the 6-18 years subpopulation. Some considerations, based on first clinical impressions, are provided in text together with comments in relation to previous and emerging literature on the topic.
2020年3月11日，意大利政府实施全国封锁以遏制新冠病毒疾病的传播。这是一项在意大利斯特拉·马里思基金会（FSM）进行的观察性纵向研究，旨在调查儿科神经精神疾病患者群体中与封锁相关的情绪和行为变化。研究人员联系了那些有1.5至18岁患有神经精神疾病且转诊至FSM的孩子的家庭，并邀请他们填写两份在线问卷（一般问卷和儿童行为检查表（CBCL）），以（i）比较（配对双样本t检验）封锁期间与之前的CBCL分数，以及（ii）研究年龄、诊断分组（神经、神经发育、情绪和行为障碍）和经济困难等变量的影响（多元线性回归模型）。141名家长填写了问卷。在1.5至5岁的亚群体中，焦虑和躯体问题增加，而在6至18岁的亚群体中，强迫、创伤后和思维问题增加。在回归模型中，1.5至5岁亚群体中较年轻的年龄显示为“保护性因素”，而家庭在封锁期间经历的经济困难与6至18岁亚群体中精神症状的增加有关。基于初步临床印象给出了一些思考，并结合了关于该主题的既往及新出现的文献进行了评论。
