由星形诺卡菌核糖核酸蛋白组分诱导的对该菌的细胞介导免疫
Cell-mediated immunity to Nocardia asteroides induced by its ribonucleic acid protein fraction.
作者信息
Sundararaj T, Agarwal S C
出版信息
Infect Immun. 1977 Oct;18(1):253-6. doi: 10.1128/iai.18.1.253-256.1977.
Abstract
Guinea pigs immunized with ribonucleic acid protein fraction from Nocardia asteroides developed high cell-mediated immunity within 2 weeks, as shown by increased macrophage microbicidal activity and macrophage migration inhibition. This immunity protected against intravenous and subcutaneous challenge with N. asteroides and persisted for at least 70 days.
摘要
用星状诺卡菌的核糖核酸蛋白组分免疫的豚鼠在2周内产生了高度的细胞介导免疫，表现为巨噬细胞杀菌活性增强和巨噬细胞游走抑制。这种免疫可保护豚鼠免受星状诺卡菌的静脉内和皮下攻击，并持续至少70天。
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