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由星形诺卡菌核糖核酸蛋白组分诱导的对该菌的细胞介导免疫

Cell-mediated immunity to Nocardia asteroides induced by its ribonucleic acid protein fraction.

作者信息

Sundararaj T, Agarwal S C

出版信息

Infect Immun. 1977 Oct;18(1):253-6. doi: 10.1128/iai.18.1.253-256.1977.

DOI:10.1128/iai.18.1.253-256.1977
PMID:332642
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC421221/
Abstract

Guinea pigs immunized with ribonucleic acid protein fraction from Nocardia asteroides developed high cell-mediated immunity within 2 weeks, as shown by increased macrophage microbicidal activity and macrophage migration inhibition. This immunity protected against intravenous and subcutaneous challenge with N. asteroides and persisted for at least 70 days.

摘要

用星状诺卡菌的核糖核酸蛋白组分免疫的豚鼠在2周内产生了高度的细胞介导免疫，表现为巨噬细胞杀菌活性增强和巨噬细胞游走抑制。这种免疫可保护豚鼠免受星状诺卡菌的静脉内和皮下攻击，并持续至少70天。

相似文献

1
Cell-mediated immunity to Nocardia asteroides induced by its ribonucleic acid protein fraction.由星形诺卡菌核糖核酸蛋白组分诱导的对该菌的细胞介导免疫
Infect Immun. 1977 Oct;18(1):253-6. doi: 10.1128/iai.18.1.253-256.1977.
2
Cell-mediated immunity in experimental Nocardia asteroides infection.实验性星形诺卡菌感染中的细胞介导免疫
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Relationship of macrophages to cell-mediated immunity in experimental Nocardia asteroides infection.实验性星形诺卡菌感染中巨噬细胞与细胞介导免疫的关系。
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Protective immunity to systemic nocardiosis in mice immunized with cell extract antigens of Nocardia asteroides.用星形诺卡菌细胞提取物抗原免疫的小鼠对全身性诺卡菌病的保护性免疫。
Med Microbiol Immunol. 1985;174(3):157-66. doi: 10.1007/BF02298126.
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[Phagocytosis and intracellular proliferation of Nocardia asteroides (strain Weipheld) in cell structures in vitro. 2. Peritoneal macrophages of guinea-pigs (author's transl)].[体外细胞结构中星形诺卡菌（魏费尔德菌株）的吞噬作用和细胞内增殖。2. 豚鼠腹膜巨噬细胞（作者译）]
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[Phagocytosis and intracellular proliferation of Nocardia asteroides (strain Weipheld) in cell structures in vitro. 1. Alveolar macrophages of guinea-pigs (author's transl)].星形诺卡菌（魏费尔德菌株）在体外细胞结构中的吞噬作用和细胞内增殖。1. 豚鼠肺泡巨噬细胞（作者译）
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引用本文的文献

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Nocardia species: host-parasite relationships.诺卡氏菌属：宿主与寄生虫的关系。
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Effects of activated macrophages on Nacardia asteroides.活化巨噬细胞对星状诺卡菌的影响。
Infect Immun. 1980 Feb;27(2):643-9. doi: 10.1128/iai.27.2.643-649.1980.
3
Protective immunity to systemic nocardiosis in mice immunized with cell extract antigens of Nocardia asteroides.用星形诺卡菌细胞提取物抗原免疫的小鼠对全身性诺卡菌病的保护性免疫。
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4
Interaction of Nocardia asteroides at different phases of growth with in vitro-maintained macrophages obtained from the lungs of normal and immunized rabbits.星形诺卡菌在不同生长阶段与从正常和免疫兔肺中获取的体外培养巨噬细胞的相互作用。
Infect Immun. 1979 Oct;26(1):355-61. doi: 10.1128/iai.26.1.355-361.1979.
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Relationship of macrophages to cell-mediated immunity in experimental Nocardia asteroides infection.实验性星形诺卡菌感染中巨噬细胞与细胞介导免疫的关系。
Infect Immun. 1978 Jun;20(3):685-91. doi: 10.1128/iai.20.3.685-691.1978.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
IMMUNOGENIC ACTIVITY OF A RIBOSOMAL FRACTION OBTAINED FROM MYCOBACTERIUM TUBERCULOSIS.从结核分枝杆菌获得的核糖体组分的免疫原活性
J Bacteriol. 1965 May;89(5):1291-8. doi: 10.1128/jb.89.5.1291-1298.1965.
3
Cell-mediated resistance induced with immunogenic preparations of Salmonella typhimurium.用鼠伤寒沙门氏菌免疫原性制剂诱导的细胞介导抗性。
Infect Immun. 1971 Oct;4(4):381-7. doi: 10.1128/iai.4.4.381-387.1971.
4
Variability of protection in inbred mice induced by a ribosomal vaccine prepared from Salmonella typhimurium.由鼠伤寒沙门氏菌制备的核糖体疫苗诱导的近交系小鼠保护作用的变异性。
Infect Immun. 1976 Sep;14(3):652-9. doi: 10.1128/iai.14.3.652-659.1976.
5
Cell-mediated immunity in experimental Nocardia asteroides infection.实验性星形诺卡菌感染中的细胞介导免疫
Infect Immun. 1977 Feb;15(2):370-5. doi: 10.1128/iai.15.2.370-375.1977.