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对纤维肌痛女性情绪及健康相关生活质量的影响。

Effects on Mood and Health-Related Quality of Life in Women with Fibromyalgia.

作者信息

Pazzi Francesco, Adsuar José Carmelo, Domínguez-Muñoz Francisco Javier, García-Gordillo Miguel Angel, Gusi Narcis, Collado-Mateo Daniel

机构信息

Health Economy Motricity and Education (HEME), Faculty of Sport Science, University of Extremadura, 10003 Cáceres, Spain.

Physical Activity and Quality of Life Research Group (AFYCAV), Faculty of Sport Science, University of Extremadura, 10003 Cáceres, Spain.

出版信息

Healthcare (Basel). 2020 Nov 30;8(4):520. doi: 10.3390/healthcare8040520.

DOI:10.3390/healthcare8040520
PMID:33265969
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7712001/
Abstract

Fibromyalgia syndrome is a chronic rheumatic disorder characterized by generalized and widespread musculoskeletal pain. It is associated with several secondary symptoms such as psychological and pain-specific distress, which can directly impact daily functioning and quality of life, like anxiety and depression. The (GL) mushroom seems to be able to improve fibromyalgia symptoms, including depression and pain. The purpose of the study is to evaluate the effects of GL on happiness, depression, satisfaction with life, and health-related quality of life in women with fibromyalgia. A double-blind, randomized placebo pilot trial was carried out, with one group taking 6 g/day of micro-milled GL carpophores for 6 weeks, during which the second group took a placebo. Our results did not show any statistically significant between-group differences, although a distinct trend of improved levels of happiness and satisfaction with life and reduced depression were evident at the end of treatment compared to the baseline in the GL group. However, due to the limitations of the study protocol, additional studies are necessary to confirm these findings.

摘要

纤维肌痛综合征是一种慢性风湿性疾病,其特征为全身性和广泛性的肌肉骨骼疼痛。它与多种继发症状相关,如心理和疼痛特异性困扰,这些会直接影响日常功能和生活质量,比如焦虑和抑郁。(GL)蘑菇似乎能够改善纤维肌痛症状,包括抑郁和疼痛。本研究的目的是评估GL对纤维肌痛女性的幸福感、抑郁、生活满意度和健康相关生活质量的影响。开展了一项双盲、随机安慰剂试点试验,一组连续6周每天服用6克微磨GL子实体,在此期间第二组服用安慰剂。我们的结果未显示出任何具有统计学意义的组间差异,尽管与基线相比,GL组在治疗结束时幸福感和生活满意度水平有所提高、抑郁有所减轻的明显趋势是显而易见的。然而,由于研究方案的局限性,需要进一步研究来证实这些发现。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3795/7712001/a278a94e9727/healthcare-08-00520-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3795/7712001/a278a94e9727/healthcare-08-00520-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3795/7712001/a278a94e9727/healthcare-08-00520-g001.jpg

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Comparison of intermittent and consecutive balneological outpatient treatment (hydrotherapy and peloidotherapy) in fibromyalgia syndrome: a randomized, single-blind, pilot study.比较纤维肌痛综合征间歇性和连续的水疗和泥疗门诊治疗(水疗法和泥疗法):一项随机、单盲、初步研究。
Int J Biometeorol. 2020 Mar;64(3):513-520. doi: 10.1007/s00484-019-01838-3. Epub 2019 Dec 4.
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Anti-inflammatory, anti-nociceptive and sedative-hypnotic activities of lucidone D extracted from Ganoderma lucidum.
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