Abbasi Hamid
Ambulatory Surgical Clinic, Tristate Brain and Spine Institute, Alexandria, USA.
Neurosurgery, Inspired Spine Health, Minneapolis, USA.
Cureus. 2020 Nov 26;12(11):e11716. doi: 10.7759/cureus.11716.
Introduction Lumbar spinal stenosis (LSS) is one of the most common indications for spinal surgery. Traditionally, decompression is achieved by removing bony and ligamentous structures through open surgery. However, recent studies have shown that symptomatic relief can be accomplished in many patients by increasing intervertebral and interpedicular height using fusion alone. In this study, we evaluate whether trans-Kambin oblique lateral lumbar interbody fusion (OLLIF) can effectively and safely relieve symptoms of LSS when an indication for fusion is present. Methods This is a retrospective single surgeon cohort study of 187 patients with LSS who underwent 189 OLLIF procedures between 2012 and August 2, 2019. Inclusion criteria for this study were age >18 years with symptoms of LSS, including pain, sensory, and motor deficits, and an additional indication for fusion, which included spondylolisthesis, degenerative disk disease, disk herniation, or scoliosis. Exclusion criteria were the bony obstruction of the approach, osteogenic spinal canal stenosis, large facet hypertrophy, and listhesis grade II or greater. The primary outcome was a change in the Oswestry Disability Index (ODI) one year after surgery. Secondary outcomes were the resolution of radiculopathy at the first follow-up visit and one year after surgery, complication rates, surgery time, blood loss, and hospital stay. Results ODI improved from 52% pre-op to 37% at the one-year follow-up. At the first follow-up, radiculopathy had resolved in 39% of patients, and 72% of patients experienced improvement of 50% or greater. One year after surgery, radiculopathy had resolved in 52% of patients and 74% experienced improvement of 50% or greater. Single-level surgeries required 56.4±21.5 minutes, with a mean hospital stay of 1.6±2.4 days. Nerve irritation occurred in 12% of patients at the first postoperative follow-up and persisted in 6.8% of patients one year after surgery. There was one case each of persistent weakness at one year, infection, and cage subsidence. Conclusion Trans-Kambin OLLIF delivers anatomic restoration of intradiscal and interpedicular distance, which results in physiologic decompression of lumbar spinal stenosis in patients undergoing lumbar fusion for degenerative or herniated disk disease, spondylolisthesis, or scoliosis. Amongst patients with LSS, OLLIF results in significant improvement of radiculopathy and patient-reported disability in the majority of patients with low rates of long-term complications. Unlike other minimally invasive surgery (MIS) fusions, OLLIF can be safely used from T12-S1.
引言
腰椎管狭窄症(LSS)是脊柱手术最常见的适应症之一。传统上,通过开放手术切除骨质和韧带结构来实现减压。然而,最近的研究表明,对于许多患者,仅通过融合增加椎间隙和椎弓根间距即可缓解症状。在本研究中,我们评估当存在融合指征时,经坎宾斜外侧腰椎椎间融合术(OLLIF)能否有效且安全地缓解LSS症状。
方法
这是一项回顾性单术者队列研究,纳入了2012年至2019年8月2日期间接受189例OLLIF手术的187例LSS患者。本研究的纳入标准为年龄>18岁,伴有LSS症状,包括疼痛、感觉和运动功能障碍,以及额外的融合指征,包括椎体滑脱、退行性椎间盘疾病、椎间盘突出或脊柱侧弯。排除标准为入路存在骨质阻挡、成骨性椎管狭窄、小关节面严重肥大以及II度或以上椎体滑脱。主要结局指标为术后1年奥斯威斯功能障碍指数(ODI)的变化。次要结局指标为首次随访和术后1年神经根病的缓解情况、并发症发生率、手术时间、失血量和住院时间。
结果
ODI从术前的52%改善至1年随访时的37%。在首次随访时,39%的患者神经根病得到缓解,72%的患者改善达50%或更高。术后1年,52%的患者神经根病得到缓解,74%的患者改善达50%或更高。单节段手术需要56.4±21.5分钟,平均住院时间为1.6±2.4天。术后首次随访时,12%的患者出现神经刺激症状,术后1年仍有6.8%的患者持续存在。术后1年分别有1例出现持续无力、感染和椎间融合器下沉。
结论
经坎宾OLLIF可实现椎间盘内和椎弓根间距的解剖学恢复,从而使因退行性或椎间盘突出疾病、椎体滑脱或脊柱侧弯接受腰椎融合术的患者的腰椎管狭窄得到生理性减压。在LSS患者中,OLLIF可使大多数患者的神经根病和患者报告的功能障碍得到显著改善,且长期并发症发生率较低。与其他微创融合手术不同,OLLIF可安全地用于T12-S1节段。