Dericks-Tan J S, Hammer E, Taubert H D
J Clin Endocrinol Metab. 1977 Sep;45(3):597-600. doi: 10.1210/jcem-45-3-597.
D-Ser (TBU)6-LH-RH-EA10 (HOE 766) was found to be approximately 40-times as effective as LH-RH in stimulating LH and FSH release in normally cyclic women. The most pronounced reaction was seen in the late follicular phase, the least one in the early follicular phase. Maximal serum gonadotropin levels were found 4 h after the injection of HOE 766. When 5 microgram was injected every 8 h for 3 days, the initially high release of LH and FSH declined progressively to almost nil.
已发现D-丝氨酸（叔丁基）6-促黄体激素释放激素-乙基酰胺10（HOE 766）在刺激正常月经周期女性促黄体激素（LH）和促卵泡激素（FSH）释放方面的效力约为促黄体激素释放激素（LH-RH）的40倍。在卵泡晚期观察到最明显的反应，在卵泡早期反应最小。注射HOE 766后4小时发现血清促性腺激素水平最高。当每8小时注射5微克，持续3天时，最初较高的LH和FSH释放逐渐下降至几乎为零。
