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血糖控制对 2 型糖尿病和非 2 型糖尿病无牙颌患者颧骨种植体存活的影响:10 年随访结果。

Influence of Glycemic Control on the Survival of Implants Placed in the Zygomatic Bone of Edentulous Patients With and Without Type 2 Diabetes Mellitus: 10-Year Follow-Up Results.

机构信息

Department of Prosthetic Dental Science, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.

Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.

出版信息

J Oral Implantol. 2022 Feb 1;48(1):21-26. doi: 10.1563/aaid-joi-D-20-00261.

DOI:10.1563/aaid-joi-D-20-00261
PMID:33270895
Abstract

It is hypothesized that under optimal glycemic control (GC), there is no difference in the survival of implants placed in the zygomatic bone of edentulous patient with and without type 2 diabetes mellitus (T2DM). The aim was to assess the influence of GC on survival of implants placed in the zygomatic bone of an edentulous patient with and without T2DM at the 10-year follow-up. Twenty patients with T2DM (10 with poorly controlled T2DM and 10 with well-controlled T2DM) and 12 patients without T2DM were included. Hemoglobin A1c (HbA1c) levels were recorded, and demographic data were collected from all participants. Peri-implant inflammatory parameters (plaque index [PI], probing depth [PD], crestal bone loss [BL], and gingival index [GI]) were measured in all patients. Group comparisons were done, and P values, which were less than .01, were indicative of statistical significance. Twenty and 12 male patients with and without T2DM, respectively, were included. Among patients with T2DM, 10 and 10 individuals had poorly and well-controlled T2DM, respectively. The mean HbA1c levels were significantly higher in patients with poorly controlled T2DM (9.2 ± 0.7%) compared with well-controlled T2DM (4.8 ± 0.3%; P < .01) and nondiabetic individuals (4.6 ± 0.3%; P < .01). The crestal BL on the mesial (P < .01) and distal (P < .01) surfaces, PD (P < .01), PI (P < .01), and GI (P < .01) were significantly higher around all zygoma implants placed in patients with poorly controlled T2DM compared with patients with well-controlled T2DM and patients without T2DM. These clinicoradiographic parameters were comparable around zygoma implants placed in patient with well-controlled T2DM and in subjects without T2DM. Optimal GC is essential for the long-term stability of zygomatic plants in patients with T2DM.

摘要

有人假设,在最佳血糖控制(GC)下,患有 2 型糖尿病(T2DM)和不患有 2 型糖尿病的无牙患者的颧骨植入物的存活率没有差异。目的是评估 GC 对患有和不患有 T2DM 的无牙患者的颧骨植入物存活率的影响,随访时间为 10 年。纳入了 20 名患有 T2DM(10 名血糖控制不佳的 T2DM 患者和 10 名血糖控制良好的 T2DM 患者)和 12 名不患有 T2DM 的患者。记录了糖化血红蛋白(HbA1c)水平,并从所有参与者中收集了人口统计学数据。所有患者均测量了种植体周围炎症参数(菌斑指数[PI]、探诊深度[PD]、牙槽骨丧失[BL]和牙龈指数[GI])。进行了组间比较,P 值小于 0.01 表示具有统计学意义。分别纳入了 20 名和 12 名患有和不患有 T2DM 的男性患者。在患有 T2DM 的患者中,分别有 10 名和 10 名患者的 T2DM 血糖控制不佳和良好。血糖控制不佳的 T2DM 患者(9.2 ± 0.7%)的平均 HbA1c 水平明显高于血糖控制良好的 T2DM 患者(4.8 ± 0.3%;P < 0.01)和非糖尿病患者(4.6 ± 0.3%;P < 0.01)。与血糖控制良好的 T2DM 患者和非糖尿病患者相比,血糖控制不佳的 T2DM 患者的所有颧骨种植体的近中(P < 0.01)和远中(P < 0.01)表面、PD(P < 0.01)、PI(P < 0.01)和 GI(P < 0.01)的牙槽骨丧失明显更高。血糖控制良好的 T2DM 患者和非糖尿病患者的颧骨种植体周围的这些临床放射参数相似。对于患有 T2DM 的患者,最佳 GC 是颧骨种植体长期稳定的关键。

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