Kuhfahl E
Abteilung Klinische Laboratorien, Bezirkskrankenhauses Dresden-Neustadt.
Z Gesamte Inn Med. 1987 Nov 15;42(22):629-33.
Hyperlipacidaemias play a role as etiological partial factor in the pathogenesis of various acute and chronic functional disturbances and are essentially the sequel of a disturbed metabolism of the free fatty acids of the fatty tissue. With regard to its clinical relevance a survey is given of the free fatty acid metabolism of the fatty tissue and its free fatty acid net balance as resultants from lipolysis and triglyceride synthesis is described. The author deals with the regulation of the lipolysis by cyclic mononucleotides, adenosine triphosphate, adenosine, fatty acids, ions, beta-hydroxybutyrate, lactate as well as hormones and finally with the control of the triglyceride synthesis.
高脂血症在各种急慢性功能紊乱的发病机制中作为病因学的部分因素发挥作用,并且本质上是脂肪组织游离脂肪酸代谢紊乱的后果。关于其临床相关性,本文综述了脂肪组织的游离脂肪酸代谢,并描述了作为脂解和甘油三酯合成结果的游离脂肪酸净平衡。作者探讨了环单核苷酸、三磷酸腺苷、腺苷、脂肪酸、离子、β-羟基丁酸、乳酸以及激素对脂解的调节,最后探讨了甘油三酯合成的控制。