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[脂肪组织中游离脂肪酸的代谢]

[Metabolism of free fatty acids in fatty tissue].

作者信息

Kuhfahl E

机构信息

Abteilung Klinische Laboratorien, Bezirkskrankenhauses Dresden-Neustadt.

出版信息

Z Gesamte Inn Med. 1987 Nov 15;42(22):629-33.

PMID:3327256
Abstract

Hyperlipacidaemias play a role as etiological partial factor in the pathogenesis of various acute and chronic functional disturbances and are essentially the sequel of a disturbed metabolism of the free fatty acids of the fatty tissue. With regard to its clinical relevance a survey is given of the free fatty acid metabolism of the fatty tissue and its free fatty acid net balance as resultants from lipolysis and triglyceride synthesis is described. The author deals with the regulation of the lipolysis by cyclic mononucleotides, adenosine triphosphate, adenosine, fatty acids, ions, beta-hydroxybutyrate, lactate as well as hormones and finally with the control of the triglyceride synthesis.

摘要

高脂血症在各种急慢性功能紊乱的发病机制中作为病因学的部分因素发挥作用,并且本质上是脂肪组织游离脂肪酸代谢紊乱的后果。关于其临床相关性,本文综述了脂肪组织的游离脂肪酸代谢,并描述了作为脂解和甘油三酯合成结果的游离脂肪酸净平衡。作者探讨了环单核苷酸、三磷酸腺苷、腺苷、脂肪酸、离子、β-羟基丁酸、乳酸以及激素对脂解的调节,最后探讨了甘油三酯合成的控制。

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Local regulation of lipolysis in adipose tissue by fatty acids, prostaglandins and adenosine.脂肪酸、前列腺素和腺苷对脂肪组织中脂肪分解的局部调节。
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Net release of individual fatty acids from white adipose tissue during lipolysis in vitro: evidence for selective fatty acid re-uptake.体外脂肪分解过程中白色脂肪组织中单个脂肪酸的净释放:脂肪酸选择性再摄取的证据。
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Role of cyclic AMP in human adipose tissue lipolysis.环磷酸腺苷在人体脂肪组织脂解中的作用。
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[Effect of insulin and glucose on lipolysis and re-esterification of free fatty acids in isolated human adipose tissue cells].
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