Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan; Department of Family Medicine, College of Medicine, China Medical University, Taichung, Taiwan.
Department of Nutrition, College of Biopharmaceutical and Food Sciences, China Medical University, Taichung, Taiwan.
Obes Res Clin Pract. 2021 Jan-Feb;15(1):58-63. doi: 10.1016/j.orcp.2020.09.007. Epub 2020 Dec 1.
Moderate-intensity exercise improves insulin sensitivity, which may depend on the intensity, duration, and frequency of exercise. We examined the effects of a single bout of short-duration high-intensity exercise (HIE) and long-duration lowintensity exercise (LIE) on insulin sensitivity and the adiponectin/leptin ratio in individuals with different body mass indices (BMIs) who do not exercise regularly.
We enrolled 42 healthy volunteers aged 20-64 years and divided them into two groups based on BMI: BMI <24 kg/m and BMI ≥27 kg/m. They were randomly assigned to either the short-duration (20 min) HIE (70%-80% heart rate reserve, HRR) or long-duration (60 min) LIE training groups (30%-40% HRR). Glucose, insulin, adiponectin, and leptin levels were assessed before training and at 0, 30, 60, and 120 min after training.
We finally analyzed 27 normal weight and 9 obese individuals. No significant differences were observed in the baseline information of both BMI groups. Homeostatic model assessment for insulin resistance significantly improved for both exercise patterns in the normal weight group and for the HIE pattern in the obese group (P < 0.01), whereas the adiponectin/leptin ratio increased significantly only among normal weight participants with the LIE intervention.
Both exercise patterns in BMI <24 kg/m and BMI ≥27 kg/m benefit on insulin resistance. Therefore, people can choose the way they can fit to improve insulin resistance both short-duration high-intensity exercise and long-duration low-intensity exercise.
中等强度的运动可以改善胰岛素敏感性，而这可能取决于运动的强度、持续时间和频率。我们研究了单次短时间高强度运动（HIE）和长时间低强度运动（LIE）对不同身体质量指数（BMI）且不经常运动的个体的胰岛素敏感性和脂联素/瘦素比值的影响。
我们招募了 42 名年龄在 20-64 岁之间的健康志愿者，并根据 BMI 将他们分为两组：BMI<24kg/m 和 BMI≥27kg/m。他们被随机分配到短时间（20 分钟）HIE（70%-80%心率储备，HRR）或长时间（60 分钟）LIE 训练组（30%-40%HRR）。在训练前和训练后 0、30、60 和 120 分钟评估血糖、胰岛素、脂联素和瘦素水平。
我们最终分析了 27 名正常体重和 9 名肥胖个体。两组 BMI 的基线信息无显著差异。正常体重组两种运动模式和肥胖组 HIE 模式的稳态模型评估胰岛素抵抗均显著改善（P<0.01），而只有 LIE 干预的正常体重参与者的脂联素/瘦素比值显著增加。
BMI<24kg/m 和 BMI≥27kg/m 的两种运动模式均有益于改善胰岛素抵抗。因此，人们可以选择适合自己的方式来改善胰岛素抵抗，既可以选择短时间高强度运动，也可以选择长时间低强度运动。
