Department of Ophthalmology, Saitama Medical University, 38 Morohongo Moroyama-machi, Iruma, Saitama, 350-0495, Japan.
Sci Rep. 2020 Dec 3;10(1):21175. doi: 10.1038/s41598-020-78147-y.
Visual field (VF) testing has usually been performed with the central gaze as a fixed point. Recent publications indicated optic nerve head deformations induced by optic nerve traction force can promote the progression of optic neuropathies, including glaucoma. We generated a new static test protocol that adds 6° adduction and abduction to gaze position (fixation points) movement. The aim of this study was to investigate both whether quantifying VF sensitivities at lateral horizontal gaze positions is feasible and whether horizontal gaze positions change sensitivities differently in subjects of different ages. Healthy adult eyes from 29 younger (≤ 45 years) and 28 elderly (> 45 years) eyes were examined in this cross-sectional study. After VF testing with central gaze as a fixation point using 24 plus (1) imo static perimetry, subjects underwent VF testing with 6° adduction and 6° abduction as fixation points. The average mean sensitivities with central gaze, adduction, and abduction were 29.9 ± 1.0, 29.9 ± 1.3, and 30.0 ± 1.2 decibels (dB) in younger subjects and 27.7 ± 1.2, 27.5 ± 1.7, and 28.1 ± 1.3 dB in elderly subjects, respectively. Visual sensitivity in young healthy subjects was similar among the three fixation points, whereas visual sensitivity in elderly healthy subjects was significantly better with abduction as a fixation point than with central gaze and adduction (both p < 0.05). We expect this test protocol to contribute to our understanding of visual function during horizontal eye gaze movement in various eye diseases.
视野 (VF) 测试通常以中央注视作为固定点进行。最近的出版物表明，视神经牵引引起的视神经头变形可促进包括青光眼在内的视神经病变的进展。我们生成了一种新的静态测试方案，该方案在注视位置 (注视点) 运动中增加了 6°内收和外展。本研究的目的是研究在水平侧方注视位置量化 VF 敏感性是否可行，以及不同年龄的受试者的水平注视位置是否会以不同的方式改变敏感性。在这项横断面研究中，检查了 29 只年轻（≤45 岁）和 28 只老年（>45 岁）眼睛的健康成人眼睛。在使用 24 加（1）imo 静态视野计以中央注视作为注视点进行 VF 测试后，受试者进行了以 6°内收和 6°外展作为注视点的 VF 测试。在年轻受试者中，中央注视、内收和外展的平均平均敏感性分别为 29.9±1.0、29.9±1.3 和 30.0±1.2 分贝 (dB)，而在老年受试者中分别为 27.7±1.2、27.5±1.7 和 28.1±1.3 dB。年轻健康受试者的三个注视点之间的视觉敏感性相似，而老年健康受试者的外展作为注视点的视觉敏感性明显优于中央注视和内收（均 p<0.05）。我们期望该测试方案有助于我们了解各种眼病中水平眼球注视运动时的视觉功能。
