Department of Psychology, University of Pennsylvania, Philadelphia, PA 19104;
Department of Neurobiology, Harvard Medical School, Boston, MA 02115.
Proc Natl Acad Sci U S A. 2020 Dec 22;117(51):32667-32678. doi: 10.1073/pnas.2018780117. Epub 2020 Dec 4.
Primate brains typically have regions within the ventral visual stream that are selectively responsive to faces. In macaques, these face patches are located in similar parts of inferotemporal cortex across individuals although correspondence with particular anatomical features has not been reported previously. Here, using high-resolution functional and anatomical imaging, we show that small "bumps," or buried gyri, along the lower bank of the superior temporal sulcus are predictive of the location of face-selective regions. Recordings from implanted multielectrode arrays verified that these bumps contain face-selective neurons. These bumps were present in monkeys raised without seeing faces and that lack face patches, indicating that these anatomical landmarks are predictive of, but not sufficient for, the presence of face selectivity. These bumps are found across primate species that span taxonomy lines, indicating common evolutionary developmental mechanisms. The bumps emerge during fetal development in macaques, indicating that they arise from general developmental mechanisms that result in the regularity of cortical folding of the entire brain.
灵长类动物的大脑通常在腹侧视觉流中有专门对脸部有反应的区域。在猕猴中，这些面部斑块位于个体间颞下皮质的相似部位，尽管以前没有报道过与特定解剖特征的对应关系。在这里，我们使用高分辨率功能和解剖成像，表明沿上颞沟下缘的小“隆起”或埋藏的脑回可预测选择性面部区域的位置。来自植入的多电极阵列的记录证实，这些隆起包含选择性面部神经元。这些隆起存在于没有看到面孔且缺乏面部斑块的猴子中，这表明这些解剖标志是可预测的，但不足以说明存在选择性面部。这些隆起存在于跨越分类学线的灵长类动物物种中，表明存在共同的进化发育机制。在猕猴中，这些隆起在胎儿发育期间出现，表明它们来自导致整个大脑皮层折叠规则性的一般发育机制。
