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与新型冠状病毒肺炎感染相关的吉兰-巴雷综合征

Guillain-Barré syndrome associated with COVID-19 infection.

作者信息

Manji Hussein Karim, George Upendo, Mkopi Namala Patrick, Manji Karim Premji

机构信息

Muhimbili University of Health and Allied Sciences, Department of Emergency Medicine, P.O. Box 65001, Dar-es-Salaam, Tanzania.

Muhimbili National Hospital, Department of Emergency Medicine, P.O. Box 65000, Dar-es-Salaam, Tanzania.

出版信息

Pan Afr Med J. 2020 Jul 18;35(Suppl 2):118. doi: 10.11604/pamj.supp.2020.35.2.25003. eCollection 2020.

Abstract

We are reporting a case of Acute Post-Infectious Flaccid paralysis also commonly known as Guillain-Barré Syndrome (GBS) in a patient with confirmed COVID-19 infection. GBS often occurs following an infectious trigger which induces autoimmune reaction causing damage to peripheral nerves. So far, only 8 cases have been described in association with COVID-19. This is the first to be described in Tanzania in an African Child, and probably the first in the continent. This report is presented for clinicians to be aware and for the medical fraternity to look into this unusual presentation which may shed some more light on possible pathways of the pathogenesis and clinical manifestations. We recommend that the presentation of GBS with acute respiratory distress should warrant extra precaution and a testing for COVID-19 especially when the symptoms of COVID-19 are protean.

摘要

我们报告了一例确诊感染新冠病毒的患者发生急性感染后弛缓性麻痹(通常也称为吉兰-巴雷综合征,GBS)的病例。GBS常发生在感染触发因素之后,该因素引发自身免疫反应,导致周围神经受损。到目前为止,仅有8例与新冠病毒感染相关的病例被描述。这是在坦桑尼亚一名非洲儿童中首次描述的病例,可能也是非洲大陆首例。本报告旨在让临床医生有所认识,并让医学界关注这种不寻常的表现,这可能会为发病机制和临床表现的可能途径提供更多线索。我们建议,对于伴有急性呼吸窘迫的GBS表现应格外谨慎,并进行新冠病毒检测,尤其是当新冠病毒症状多变时。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/657f/7687474/25d985bc277e/PAMJ-SUPP-35-2-118-g001.jpg

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