Broitman Adam W, Kahana Michael J, Healey M Karl
Cornell University.
University of Pennsylvania.
Comput Brain Behav. 2020 Jun;3(2):200-207. doi: 10.1007/s42113-019-00047-w. Epub 2019 Aug 14.
Longitudinal designs must deal with the confound between increasing age and increasing task experience (i.e., retest effects). Most existing methods for disentangling these factors rely on large sample sizes and are impractical for smaller scale projects. Here, we show that a measurement burst design combined with a model of retest effects can be used to study age-related change with modest sample sizes. A combined model of age-related change and retest-related effects was developed. In a simulation experiment, we show that with sample sizes as small as = 8, the model can reliably detect age effects of the size reported in the longitudinal literature while avoiding false positives when there is no age effect. We applied the model to data from a measurement burst study in which eight subjects completed a burst of seven sessions of free recall every year for five years. Six additional subjects completed a burst only in years 1 and 5. They should, therefore, have smaller retest effects but equal age effects. The raw data suggested slight improvement in memory over five years. However, applying the model to the yearly-testing group revealed that a substantial positive retest effect was obscuring stability in memory performance. Supporting this finding, the control group showed a smaller retest effect but an equal age effect. Measurement burst designs combined with models of retest effects allow researchers to employ longitudinal designs in areas where previously only cross-sectional designs were feasible.
纵向设计必须应对年龄增长与任务经验增加之间的混淆因素(即重测效应)。大多数现有的区分这些因素的方法依赖于大样本量,对于较小规模的项目来说不切实际。在这里,我们表明,测量突发设计与重测效应模型相结合,可以用于在样本量适中的情况下研究与年龄相关的变化。我们开发了一个与年龄相关变化和重测相关效应的组合模型。在一个模拟实验中,我们表明,当样本量小至 = 8时,该模型能够可靠地检测纵向文献中报道的那种规模的年龄效应,同时在不存在年龄效应时避免误报。我们将该模型应用于一项测量突发研究的数据,在该研究中,八名受试者在五年内每年完成七次自由回忆测试的突发测试。另外六名受试者仅在第1年和第5年完成了一次突发测试。因此,他们的重测效应应该较小,但年龄效应相同。原始数据表明五年内记忆力略有改善。然而,将该模型应用于年度测试组发现,显著的正向重测效应掩盖了记忆表现的稳定性。支持这一发现的是,对照组显示出较小的重测效应,但年龄效应相同。测量突发设计与重测效应模型相结合,使研究人员能够在以前只有横断面设计可行的领域采用纵向设计。