Coscia Alessandra, Boscarino Giovanni, Di Chiara Maria, Faccioli Francesca, Pedicino Roberto, Onestà Elisa, Giancotti Antonella, Di Donato Violante, Ronchi Benedetta, Zantonelli Francesca, Russo Alessia, Mezzapiastra Chiara, Terrin Gianluca
Neonatology Unit, Department of Public Health and Pediatrics, University of Turin, Turin, Italy.
Department of Maternal and Child Health Policlinico Umberto I, University La Sapienza, Rome, Italy.
Eur J Pediatr. 2021 Feb;180(2):505-511. doi: 10.1007/s00431-020-03889-w. Epub 2020 Dec 7.
Umbilical cord care can be a stressful practice for parents. Complications of cord care can increase neonatal morbidity and mortality. The extracts of Arnica montana (AM) have been reported to possess antibacterial, anti-inflammatory, antifungal, and immunomodulatory activities. We aim to demonstrate the efficacy of AM on cord detachment and parents' stress level induced by cord medication in healthy full-term newborns. We enrolled full-term infants with a birth weight ≥ 2500 g in healthy conditions. Cord stumps of infants in the PRE-group were cleaned and dried, while cord stumps of infants in the POST-group were cleaned, dried, and medicated with a natural topic dermo-protective powder containing AM. After discharge, we interviewed parents on the stump status during follow-up visits in a pediatric office at 7 and 14 days of life, or by phone calls after follow-up visits. Long-rank test showed that time of cord separation of newborns in the PRE-group was significantly higher compared to that in the POST-group (p < 0.001). Parents of newborns in the PRE-group were significantly more stressed during cord medication compared to parents in the POST-group (2.0 (1.2 to 2.1) vs 1.0 (0.8 to 1.3), p = 0.011). Multivariate analysis showed a significantly linear relation with group assignment for cord separation (p < 0.001) and parents' stress during the medication (p = 0.033).Conclusion: The use of a natural topic dermo-protective powder containing AM reduces the time of cord separation, improves parents' stress level, and reduces the risk of complications. What is Known: • Cord stump care can be a stressful practice for parents. • Antiseptic treatment recommended for cord care could be associated with side effects such as burning and sensitization. What is New: • The medication of cord stump with a natural topic dermo-protective powder containing Arnica montana reduces time of cord detachment and of complication such as redness', bleeding, or secretions. • The use of Arnica montana for cord medication may have a positive impact on the family, reducing parents' stress, and the use of other medications.
脐带护理对父母来说可能是一项压力较大的操作。脐带护理的并发症会增加新生儿的发病率和死亡率。据报道，山金车（AM）提取物具有抗菌、抗炎、抗真菌和免疫调节活性。我们旨在证明AM对健康足月儿脐带脱落以及脐带用药引起的父母压力水平的疗效。我们纳入了出生体重≥2500g的健康足月儿。PRE组婴儿的脐带残端进行清洁和干燥处理，而POST组婴儿的脐带残端进行清洁、干燥，并使用含AM的天然局部皮肤保护粉进行用药处理。出院后，我们在婴儿出生7天和14天时于儿科诊所的随访中，或在随访后通过电话采访父母了解脐带残端状况。秩和检验显示，PRE组新生儿的脐带脱落时间显著长于POST组（p<0.001）。与POST组的父母相比，PRE组新生儿的父母在脐带用药期间压力明显更大（2.0（1.2至2.1）对1.0（0.8至1.3），p = 0.011）。多因素分析显示，脐带脱落与分组（p<0.001）以及用药期间父母的压力（p = 0.033）之间存在显著的线性关系。结论：使用含AM的天然局部皮肤保护粉可缩短脐带脱落时间，改善父母的压力水平，并降低并发症风险。已知信息：• 脐带残端护理对父母来说可能是一项压力较大的操作。• 推荐用于脐带护理的抗菌治疗可能会伴有烧灼感和过敏等副作用。新发现：• 使用含山金车的天然局部皮肤保护粉处理脐带残端可缩短脐带脱落时间，并减少发红、出血或分泌物等并发症。• 使用山金车进行脐带用药可能对家庭有积极影响，减轻父母的压力，并减少其他药物的使用。
