Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Department of Pediatrics, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
Diagn Interv Radiol. 2021 Jan;27(1):42-49. doi: 10.5152/dir.2020.19633.
We investigated the impact of model-based iterative reconstruction (MBIR) on 320-detector row computed tomography angiography (CTA) in infants with complex congenital heart disease (CHD).
Seventy infants with complex CHD who underwent 320-detector row CTA (40 boys and 30 girls; age range, 0-22 months; median age, 60 days) were retrospectively evaluated. First, the images were reconstructed by filtered back projection (FBP), hybrid iterative reconstruction (HIR), or MBIR in 20 cases, and variables were compared among the three iterative reconstruction methods (IR test). Second, the variables were compared between 25 cases scanned using HIR and 25 cases scanned using MBIR, with a 20 standard deviation noise level for both. Attenuation values and contrast-to-noise ratios (CNRs) of the great vessels and heart chambers were calculated. Total dose-length products were recorded for all patients (radiation dose: RD test).
In the IR test, the mean CNR values were 4.8±1.3 for FBP, 6.9±1.4 for HIR, and 8.2±1.7 for MBIR (P < 0.0001). The best subjective image qualities in the great vessels and heart chambers were obtained with MBIR. In RD testing, no significant differences between HIR and MBIR in image quality (CNR: HIR, 8.4±2.4; MBIR, 8.3±2.4) were observed. The effective dose was significantly lower for MBIR than for HIR (0.7±0.2 vs. 1.1±0.3 mSv; P < 0.001).
The MBIR algorithm significantly improved image quality and decreased radiation exposure in 320-row CTA of infants with complex CHD, providing an alternative to FBP or HIR that is both safer and produces better results.
我们研究了基于模型的迭代重建（MBIR）对患有复杂先天性心脏病（CHD）的婴儿进行 320 排 CT 血管造影（CTA）的影响。
回顾性分析了 70 例患有复杂 CHD 的婴儿（男 40 例，女 30 例；年龄 0-22 个月；中位年龄 60 天）的 320 排 CTA 检查结果。首先，在 20 例患者中分别采用滤波反投影（FBP）、混合迭代重建（HIR）和 MBIR 进行图像重建，比较三种迭代重建方法的各项参数（IR 测试）。然后，对 25 例采用 HIR 扫描的患者和 25 例采用 MBIR 扫描的患者的各项参数进行比较，两种重建方法噪声水平均为 20 个标准差。测量大血管和心脏腔室的衰减值和对比噪声比（CNR）。记录所有患者的剂量长度乘积（辐射剂量：RD 测试）。
在 IR 测试中，FBP、HIR 和 MBIR 的平均 CNR 值分别为 4.8±1.3、6.9±1.4 和 8.2±1.7（P<0.0001）。MBIR 可获得最佳的大血管和心脏腔室主观图像质量。在 RD 测试中，HIR 和 MBIR 之间的图像质量（CNR：HIR 为 8.4±2.4，MBIR 为 8.3±2.4）无显著差异。MBIR 的有效剂量明显低于 HIR（0.7±0.2 比 1.1±0.3 mSv；P<0.001）。
MBIR 算法显著提高了复杂 CHD 婴儿 320 排 CTA 的图像质量并降低了辐射暴露，为 FBP 或 HIR 提供了一种更安全、效果更好的替代方案。
