Regional Burn Center, Lehigh Valley Health Network, Allentown, PA, USA.
Regional Burn Center, Lehigh Valley Health Network, Allentown, PA, USA.
Burns. 2021 Jun;47(4):838-846. doi: 10.1016/j.burns.2020.08.008. Epub 2020 Aug 29.
A new bio-degradable synthetic membrane was recently introduced to treat second degree burns in adults and pediatric patients.
To assess complications and outcomes using this absorbable synthetic membrane to treat second degree burns.
229 burn patients, 138 pediatric, with superficial and deep second -degree wounds, treated with the absorbable synthetic membrane (Suprathel®, Polymedics, Denkendorf, Germany) were included in this study. Patients were treated under anesthesia or moderate sedation. The wound bed was prepared by using either rough debridement or dermabrasion excision. After hemostasis, the membrane was applied to the wound with an outer layer dressing of fatty gauze, bridal veil, absorptive gauze and an ACE® wrap. The outer dressing was removed every one to four days, depending on exudate, in order to closely follow the wound through the translucent membrane and fatty gauze layers. After complete epithelialization, the dressing separated and could be removed. The study focused on the need for subsequent grafting, healing time, patient pain level, hypertrophic scarring and rate of infection.
All wounds in this study that were treated with Suprathel® healed without grafting. The average TBSA (Total Body Surface Area) was 8.9% (1%-60%). Average time to healing was 13.7 days for ≥ 90% epithelialization with 11.9 days for pediatric patients versus 14.7 days for adults. Throughout the treatment period, the average pain level was 1.9 on a 10-point scale. 27 patients developed hypertrophic scarring in some areas (11.7%). Average Length of stay (LOS) was 6.9 days. The rate of infection was 3.8% (8/229). Failure or progression to full thickness in part of the wounds was 5.2% (12/229).
In treating second degree burn wounds, this membrane provides a simple, effective solution alternative with good outcomes and less pain than conventional and previously studied treatment options in the same institution. Fewer dressing changes and easier overall management of the wounds contribute to its favorable profile.
最近引入了一种新的可生物降解的合成膜,用于治疗成人和儿科患者的二度烧伤。
评估使用这种可吸收合成膜治疗二度烧伤的并发症和结果。
本研究纳入了 229 例烧伤患者,其中 138 例为儿科患者,有浅二度和深二度创面,使用可吸收合成膜(Suprathel®,Polymedics,Denkendorf,德国)治疗。患者在全身麻醉或中度镇静下接受治疗。用粗糙清创或表皮切除术准备创面床。止血后,将膜应用于创面,外层敷料为脂肪纱布、新娘面纱、吸收性纱布和 ACE®包裹。根据渗出物的情况,每 1-4 天更换外层敷料,以便通过半透明膜和脂肪纱布层密切观察创面。完全上皮化后,敷料分离并可去除。该研究主要关注后续植皮的需要、愈合时间、患者疼痛程度、增生性瘢痕形成和感染率。
本研究中使用 Suprathel®治疗的所有创面均无需植皮愈合。平均 TBSA(总体表面积)为 8.9%(1%-60%)。≥90%上皮化的平均愈合时间为 13.7 天,儿科患者为 11.9 天,成人患者为 14.7 天。整个治疗期间,平均疼痛水平为 10 分制的 1.9 分。27 例患者在某些部位出现增生性瘢痕(11.7%)。平均住院时间(LOS)为 6.9 天。感染率为 3.8%(8/229)。部分创面完全或部分愈合失败或进展的发生率为 5.2%(12/229)。
在治疗二度烧伤创面时,与同一机构的传统和先前研究的治疗选择相比,这种膜提供了一种简单、有效的替代方案,具有良好的结果和较少的疼痛。较少的换药和更简单的创面整体管理有助于其良好的效果。