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Full scalp hair regrowth in a 4-year-old girl with alopecia areata and atopic dermatitis treated with dupilumab.

作者信息

Gruenstein Diana, Malik Kunal, Levitt Jacob

机构信息

Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York.

出版信息

JAAD Case Rep. 2020 Oct 15;6(12):1286-1287. doi: 10.1016/j.jdcr.2020.10.010. eCollection 2020 Dec.

DOI:10.1016/j.jdcr.2020.10.010
PMID:33294565
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7701016/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b8/7701016/7b70237d8c8d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b8/7701016/7b70237d8c8d/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b8/7701016/7b70237d8c8d/gr1.jpg

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Full scalp hair regrowth in a 4-year-old girl with alopecia areata and atopic dermatitis treated with dupilumab.用度普利尤单抗治疗的一名患有斑秃和特应性皮炎的4岁女孩头皮毛发完全再生。
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[Hair growth with dupilumab in alopecia areata universalis and atopic dermatitis].[度普利尤单抗治疗泛发性斑秃和特应性皮炎时的毛发生长]
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4
Scalp biomarkers during dupilumab treatment support Th2 pathway pathogenicity in alopecia areata.在治疗斑秃时，头皮生物标志物支持白细胞介素-35 通路在发病机制中的作用。
Allergy. 2023 Apr;78(4):1047-1059. doi: 10.1111/all.15561. Epub 2022 Nov 5.
5
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[Dupilumab-Associated Healing of Alopecia Areata in an Atopic Dermatitis Patient].[特应性皮炎患者中与度普利尤单抗相关的斑秃愈合情况]
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本文引用的文献

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Alopecia Areata Is Associated with Atopic Diathesis: Results from a Population-Based Study of 51,561 Patients.斑秃与特应性素质相关：基于51561例患者的人群研究结果
J Allergy Clin Immunol Pract. 2020 Apr;8(4):1323-1328.e1. doi: 10.1016/j.jaip.2020.01.052. Epub 2020 Feb 6.
2
The utility of dupilumab for use in the pediatric population.度普利尤单抗在儿科人群中的应用效用。
JAAD Case Rep. 2019 Oct 24;5(11):943-944. doi: 10.1016/j.jdcr.2019.08.023. eCollection 2019 Nov.
3
Efficacy and Safety of Dupilumab in Adolescents With Uncontrolled Moderate to Severe Atopic Dermatitis: A Phase 3 Randomized Clinical Trial.
度普利尤单抗可诱导儿童斑秃毛发再生：一项真实世界、单中心观察性研究。
Arch Dermatol Res. 2024 Jul 23;316(7):487. doi: 10.1007/s00403-024-03225-4.
4
Biologics and small molecules treatment for moderate-to-severe atopic dermatitis patients with comorbid conditions and special populations: an Italian perspective.合并症和特殊人群的中重度特应性皮炎患者的生物制剂和小分子治疗：意大利视角
Dermatol Reports. 2023 Sep 13;16(2):9839. doi: 10.4081/dr.2023.9839. eCollection 2024 Jun 14.
5
Dupilumab in Inflammatory Skin Diseases: A Systematic Review.度普利尤单抗治疗炎症性皮肤病：系统评价。
Biomolecules. 2023 Mar 31;13(4):634. doi: 10.3390/biom13040634.
6
Improvement of atopic dermatitis and alopecia universalis with dupilumab.度普利尤单抗治疗特应性皮炎和泛发性斑秃的疗效观察
Dermatol Reports. 2021 Dec 28;14(2):9359. doi: 10.4081/dr.2022.9359. eCollection 2022 Jun 16.
7
An Overview of Off-Label Use of Humanized Monoclonal Antibodies in Paediatrics.人源化单克隆抗体在儿科领域的超说明书使用概述。
Medicina (Kaunas). 2022 Apr 29;58(5):625. doi: 10.3390/medicina58050625.
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Resolution of dupilumab-associated alopecia areata with dosage modification.通过调整度普利尤单抗剂量使斑秃得到缓解。
JAAD Case Rep. 2022 Feb 17;22:85-88. doi: 10.1016/j.jdcr.2022.01.034. eCollection 2022 Apr.
9
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Skin Appendage Disord. 2022 Jan;8(1):38-41. doi: 10.1159/000517832. Epub 2021 Jul 27.
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JAMA Dermatol. 2020 Jan 1;156(1):44-56. doi: 10.1001/jamadermatol.2019.3336.
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Hair Regrowth in a Patient With Long-standing Alopecia Totalis and Atopic Dermatitis Treated With Dupilumab.使用度普利尤单抗治疗的长期全秃和特应性皮炎患者的毛发再生
JAMA Dermatol. 2018 Nov 1;154(11):1358-1360. doi: 10.1001/jamadermatol.2018.2976.
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An integrated model of alopecia areata biomarkers highlights both T1 and T2 upregulation.斑秃生物标志物的综合模型突出了T1和T2的上调。
J Allergy Clin Immunol. 2018 Nov;142(5):1631-1634.e13. doi: 10.1016/j.jaci.2018.06.029. Epub 2018 Jul 5.
6
Alopecia areata after dupilumab for atopic dermatitis.度普利尤单抗治疗特应性皮炎后出现斑秃。
JAAD Case Rep. 2018 Jan 16;4(2):143-144. doi: 10.1016/j.jdcr.2017.11.020. eCollection 2018 Mar.
7
A novel therapeutic paradigm for patients with extensive alopecia areata.一种治疗广泛性斑秃患者的新疗法。
Expert Opin Biol Ther. 2016 Aug;16(8):1005-14. doi: 10.1080/14712598.2016.1188076. Epub 2016 May 30.
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Alopecia areata profiling shows TH1, TH2, and IL-23 cytokine activation without parallel TH17/TH22 skewing.斑秃特征分析显示 TH1、TH2 和 IL-23 细胞因子激活，而无平行的 TH17/TH22 偏倚。
J Allergy Clin Immunol. 2015 Nov;136(5):1277-87. doi: 10.1016/j.jaci.2015.06.032. Epub 2015 Aug 24.
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The association between Interleukin (IL)-4 gene intron 3 VNTR polymorphism and alopecia areata (AA) in Turkish population.白细胞介素 (IL)-4 基因内含子 3 VNTR 多态性与土耳其人群斑秃的相关性。
Gene. 2013 Sep 25;527(2):565-9. doi: 10.1016/j.gene.2013.05.086. Epub 2013 Jul 4.
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Follow-up study of the first genome-wide association scan in alopecia areata: IL13 and KIAA0350 as susceptibility loci supported with genome-wide significance.斑秃全基因组关联扫描的随访研究：IL13 和 KIAA0350 作为易感性基因座，具有全基因组显著性意义。
J Invest Dermatol. 2012 Sep;132(9):2192-7. doi: 10.1038/jid.2012.129. Epub 2012 Apr 26.