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Watch-PAT在房颤患者睡眠呼吸暂停的诊断中很有用。

Watch-PAT is Useful in the Diagnosis of Sleep Apnea in Patients with Atrial Fibrillation.

作者信息

Tauman Riva, Berall Murray, Berry Richard, Etzioni Tamar, Shrater Noam, Hwang Dennis, Marai Ibrahim, Manthena Prasanth, Rama Anil, Spiegel Rebecca, Penzel Thomas, Koren Morag Nira, Pillar Giora

机构信息

Sleep Disorders Center, Tel Aviv Souraski Medical Center, Tel Aviv, Israel.

Center of Sleep and Chronobiology, Toronto, ON, Canada.

出版信息

Nat Sci Sleep. 2020 Dec 3;12:1115-1121. doi: 10.2147/NSS.S278752. eCollection 2020.

Abstract

BACKGROUND

Early diagnosis and treatment of sleep apnea in patients with atrial fibrillation (AF) is critical. The WatchPAT (WP) device was shown to be accurate for the diagnosis of sleep apnea; however, studies using the WatchPAT device have thus far excluded patients with arrhythmias due to the potential effect of arrhythmias on the peripheral arterial tonometry (PAT) amplitude and pulse rate changes.

PURPOSE

To examine the accuracy of the WP in detecting sleep apnea in patients with AF.

PATIENTS AND METHODS

Patients with AF underwent simultaneous WP and PSG studies in 11 sleep centers. PSG scoring was blinded to the automatically analyzed WP data.

RESULTS

A total of 101 patients with AF (70 males) were recruited. Forty-six had AF episodes during the overnight sleep study. A significant correlation was found between the PSG-derived AHI and the WP- derived AHI (r=0.80, p<0.0001). There was a good agreement between PSG-derived AHI and WP-derived AHI (mean difference of AHI: -0.02±13.2). Using a threshold of AHI ≥15 per hour of sleep, the sensitivity and specificity of the WP were 0.88 and 0.63, respectively. The overall accuracy in sleep staging between WP and PSG was 62% with Kappa agreement of 0.42.

CONCLUSION

WP can detect sleep apnea events in patients with AF. AF should not be an exclusion criterion for using the device. This finding may be of even greater importance in the era of the COVID19 epidemic, when sleep labs were closed and most studies were home based.

摘要

背景

心房颤动(AF)患者睡眠呼吸暂停的早期诊断和治疗至关重要。研究表明,WatchPAT(WP)设备在诊断睡眠呼吸暂停方面具有准确性;然而,由于心律失常对周围动脉张力测定(PAT)幅度和脉搏率变化的潜在影响,迄今为止使用WP设备的研究排除了心律失常患者。

目的

研究WP设备在检测AF患者睡眠呼吸暂停方面的准确性。

患者与方法

11个睡眠中心的AF患者同时接受了WP和多导睡眠图(PSG)检查。PSG评分对自动分析的WP数据不知情。

结果

共招募了101例AF患者(70例男性)。46例患者在夜间睡眠研究期间出现AF发作。PSG得出的呼吸暂停低通气指数(AHI)与WP得出的AHI之间存在显著相关性(r = 0.80,p < 0.0001)。PSG得出的AHI与WP得出的AHI之间具有良好的一致性(AHI的平均差异:-0.02±13.2)。使用每小时睡眠AHI≥15的阈值,WP的敏感性和特异性分别为0.88和0.63。WP和PSG在睡眠分期方面的总体准确率为62%,Kappa一致性为0.42。

结论

WP可以检测AF患者的睡眠呼吸暂停事件。AF不应成为使用该设备的排除标准。在2019冠状病毒病流行时代,当睡眠实验室关闭且大多数研究基于家庭进行时,这一发现可能更为重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c75f/7721305/d159323d7c3c/NSS-12-1115-g0001.jpg

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