Department of Emergency Medicine, Second Xiangya Hospital, Central South University, Changsha, China.
Emergency Medicine and Difficult Diseases Institute, Second Xiangya Hospital, Central South University, Changsha, China.
Behav Neurol. 2020 Nov 22;2020:9624106. doi: 10.1155/2020/9624106. eCollection 2020.
To estimate the relationship between obesity (defined by both BMI and SAD) and various levels of depressive symptoms in women in the United States.
This is a cross-sectional design. All data were collected from NHANES 2011-2012 and 2013-2014. The Patient Health Questionnaire (PHQ-9) was the primary variable used to index depressive symptoms. SAD was assessed using an abdominal caliper. We stratified participates into three groups according to SAD (trisection): T1: low (11.8-18.4 cm), T2: middle (18.5-22.8 cm), and T3: high (22.9-40.1 cm). Other data were collected following the NHANES protocols. We aimed to investigate the effects of obesity on the depression in the NHANES populations.
A total of 4477 women were enrolled in the final study population. Participants with a high SAD had the highest risk of clinical depression symptoms (OR = 1.2, 95% CI: 1.1-1.4), which was, in particular, the case for moderate-severe depression (OR = 1.4, 95% CI: 1.1-1.7) and severe depression (OR = 1.4, 95% CI: 1.0-1.9). We also found a significant relationship between SAD and BMI ( = 0.836). We did, however, not find a significant relationship between BMI and severe depression.
SAD had a better correlation with clinical depression symptoms than BMI, especially regarding severe depression symptoms.
评估肥胖(通过 BMI 和 SAD 定义)与美国女性不同程度抑郁症状之间的关系。
这是一项横断面设计。所有数据均来自 NHANES 2011-2012 年和 2013-2014 年。使用患者健康问卷(PHQ-9)作为主要变量来评估抑郁症状。使用腹部卡尺评估 SAD。我们根据 SAD(三分位)将参与者分为三组:T1:低(11.8-18.4cm),T2:中(18.5-22.8cm),T3:高(22.9-40.1cm)。其他数据按照 NHANES 协议收集。我们旨在研究肥胖对 NHANES 人群中抑郁的影响。
共有 4477 名女性被纳入最终的研究人群。SAD 较高的参与者患临床抑郁症状的风险最高(OR=1.2,95%CI:1.1-1.4),尤其是中重度抑郁(OR=1.4,95%CI:1.1-1.7)和重度抑郁(OR=1.4,95%CI:1.0-1.9)。我们还发现 SAD 与 BMI 之间存在显著关系(=0.836)。然而,我们没有发现 BMI 与重度抑郁之间存在显著关系。
SAD 与临床抑郁症状的相关性优于 BMI,尤其是与重度抑郁症状的相关性。