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原发性皮肤诺卡菌病患者的MRI表现:一例报告

MRI findings in patient with primary cutaneous nocardiosis: A case report.

作者信息

Reginelli Alfonso, Russo Anna, Pignatiello Maria, Patanè Vittorio, Laterza Fabio, Monti Riccardo, Urraro Fabrizio, Caliendo Valentina, Cappabianca Salvatore

机构信息

Dipartimento di Medicina di Precisione, Università degli Studi della Campania "Luigi Vanvitelli," Piazza Luigi Miraglia 2 80138 Naples, Italy.

出版信息

Radiol Case Rep. 2023 Apr 11;18(6):2199-2203. doi: 10.1016/j.radcr.2023.03.005. eCollection 2023 Jun.

Abstract

Nocardia is a genus of gram-positive, filamentous, aerobic bacteria that belongs to the Actinomycetales order. With over 50 species, it is ubiquitous in dust, soil, decaying organic matter, and stagnant water. Inhalation of the pathogen often leads to pulmonary nocardiosis, while extrapulmonary nocardiosis can affect the central nervous system, skin, and subcutaneous tissues. Primary cutaneous nocardiosis occurs when the pathogen is introduced through a skin lesion or insect bite, for example, this report presents a case of primary cutaneous nocardiosis in a patient with Minimal Change Glomerulonephritis and iatrogenic immunosuppression. Magnetic resonance imaging revealed extensive involvement of the skin, subcutaneous tissue, and lower limb muscles.

摘要

诺卡菌属是革兰氏阳性、丝状、需氧细菌,属于放线菌目。它有50多个种,普遍存在于灰尘、土壤、腐烂的有机物和死水中。吸入该病原体常导致肺诺卡菌病,而肺外诺卡菌病可影响中枢神经系统、皮肤和皮下组织。原发性皮肤诺卡菌病是病原体通过皮肤损伤或昆虫叮咬侵入人体时发生的,例如,本报告介绍了一例患有微小病变性肾小球肾炎和医源性免疫抑制的患者发生原发性皮肤诺卡菌病的病例。磁共振成像显示皮肤、皮下组织和下肢肌肉广泛受累。

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