Goodall Richard, Armstrong Alexander, Hughes William, Fries Charles A, Marshall Dominic, Harbinson Eleanor B, Salciccioli Justin, Shalhoub Joseph
Imperial College London, London, UK.
Department of Plastic Surgery, Oxford University Hospitals NHS Foundation Trust, UK.
Plast Reconstr Surg Glob Open. 2020 Nov 23;8(11):e3252. doi: 10.1097/GOX.0000000000003252. eCollection 2020 Nov.
Decubitus ulcers (DU) are a common pathology with significant morbidity and financial implications for health services globally. This study aimed to compare the burden of DU across European Union (EU) 15+ countries between 1990 and 2017.
Age-standardized incidence, mortality, and disability-adjusted life-years (DALYs) rates per 100,000 were extracted from the Global Burden of Disease Study online data repository for EU15+ countries (a group of 19 countries with comparable health expenditure, including the United States, Canada, the United Kingdom, and Australia). A joinpoint regression analysis was used to describe trends.
The incidence of DU increased between 1990 and 2017 in 15 of 19 EU15+ countries for both men and women. Mortality from DU decreased over the time period analyzed in the majority of EU15+ countries: only in Denmark, Finland, and Germany were increasing mortality rates observed. Decreasing DALY rates were generally observed, with the largest decreases observed in Ireland for men and women. Denmark and Germany were the only countries to demonstrate unfavorable trends in mortality, incidence, and DALYs between 1990 and 2017 for men and women. The United States, the Netherlands, and France were the only EU15+ countries in which improving disease burden was identified between 1990 and 2017 for all parameters assessed.
Incidence of DU is increasing in EU15+ countries, whereas mortality rates and DALYs are improving. The trends in disease burden in Denmark and Germany have followed contrasting and unfavorable trends. Investigation into these trends is called for.
压疮（DU）是一种常见的病理状况，对全球卫生服务具有重大的发病率影响和经济影响。本研究旨在比较1990年至2017年期间欧盟（EU）15个以上国家压疮的负担情况。
从全球疾病负担研究在线数据存储库中提取欧盟15个以上国家（一组19个卫生支出相当的国家，包括美国、加拿大、英国和澳大利亚）每10万人的年龄标准化发病率、死亡率和伤残调整生命年（DALY）率。采用连接点回归分析来描述趋势。
在19个欧盟15个以上国家中的15个国家，1990年至2017年期间男性和女性的压疮发病率均有所上升。在大多数欧盟15个以上国家，在所分析的时间段内压疮死亡率有所下降：仅在丹麦、芬兰和德国观察到死亡率上升。总体上观察到达利率下降，其中爱尔兰男性和女性的下降幅度最大。丹麦和德国是1990年至2017年期间男性和女性在死亡率、发病率和DALYs方面仅有的呈现不利趋势的国家。美国、荷兰和法国是1990年至2017年期间在所评估的所有参数方面疾病负担得到改善的仅有的欧盟15个以上国家。
欧盟15个以上国家压疮的发病率在上升，而死亡率和伤残调整生命年在改善。丹麦和德国疾病负担的趋势呈现出相反且不利的趋势。需要对这些趋势进行调查。
